首页> 外文期刊>Clinical and experimental allergy : >Prevalence and longitudinal trends of food allergy during childhood and adolescence: Results of the Isle of Wight Birth Cohort study
【24h】

Prevalence and longitudinal trends of food allergy during childhood and adolescence: Results of the Isle of Wight Birth Cohort study

机译:儿童与青春期食物过敏的患病率和纵向趋势:怀特生队队列的结果

获取原文
获取原文并翻译 | 示例
           

摘要

Summary Background The prevalence and time trends of food allergy change during childhood depending on the age of the child and the type of food. Objective To study prevalence and longitudinal trends in food allergy from birth to 18?years in an unselected birth cohort in the Isle of Wight. Method Information on food allergy was collected at ages 1, 2, 4, 10 and 18?years from the Isle of Wight Birth Cohort (n?=?1456). Skin prick testing ( SPT ) was performed at the age of 1 and 2?years in symptomatic children. At 4, 10 and 18?years of age, participants were tested to a panel of food and aeroallergens. Food allergy was diagnosed based on the criteria: symptoms suggestive of a typical IgE‐mediated reaction and reaction 4?hours following exposure to a known food allergen. McNemar's test was used to determine significance of changes in prevalence over time. Results The prevalence of food allergy remained relatively constant in early childhood (5.3%, 4.4% and 5.0% at 1, 2 and 4?years, respectively), with significant decline at 10?years (2.3%, P ??.001 vs 4?years) followed by significant rise at 18?years (4%, P ?=?.02 vs 10?years). Cow's milk (1.6%‐3.5%) and egg (1.1%‐1.4%) were the most common allergens in the first 10?years with peanut (1%) and tree nuts (0.5%) becoming more prevalent beyond 10?years. Fruit and wheat allergy were less common at 10?years, and shellfish and kiwi emerged during adolescence. The prevalence of food allergy plus positive SPT was 1.3%, 0.8%, 0.8%, 0.9% and 2.2% at 1, 2, 4, 10 and 18?years, respectively. Conclusion Food allergy is highly prevalent in infancy with partial resolution during late childhood. However, a number of children acquire new food allergy during adolescence resulting in a relatively higher prevalence at 18?years.
机译:None

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号