Decrease in CD38(+) TH2A cell frequencies following immunotherapy with house dust mite tablet correlates with humoral responses

Luce Sonia; Batard Thierry; Bordas-Le Floch Veronique; Le Gall Martine; Mascarell Laurent

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Decrease in CD38(+) TH2A cell frequencies following immunotherapy with house dust mite tablet correlates with humoral responses

机译：随着房屋粉尘螨片剂的免疫疗法，CD38（+）TH2A细胞频率降低了与液体反应相关

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Background In line with evidence for a role of pathogenic TH2A in seasonal allergies, we previously showed that individuals suffering from food allergy exhibited a decrease in circulating TH2A cells following multi-food immunotherapy. Herein, we aim to confirm the decline of TH2A cells in individuals undergoing house dust mite immunotherapy (HDM-AIT) and extend our observation to a new subset of CD38 expressing activated TH2A cells.

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来源
《Clinical and experimental allergy :》 |2021年第8期|共12页
作者
Luce Sonia; Batard Thierry; Bordas-Le Floch Veronique; Le Gall Martine; Mascarell Laurent;
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作者单位

Stallergenes Greer Antony France;

Stallergenes Greer Antony France;

Stallergenes Greer Antony France;

Stallergenes Greer Antony France;

Stallergenes Greer Antony France;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
CD38(+)TH2A; house dust mite; sublingual immunotherapy;

机译：CD38（+）TH2A;房子尘螨;舌下免疫疗法;

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专利

1. Effect of house dust mite immunotherapy on interleukin-10-secreting regulatory T cells in asthmatic children [J] . WANG Wei, XIANG Li, LIU Yong-ge, 中华医学杂志：英文版 . 2010,第015期
2. Effect of house dust mite immunotherapy on interleukin-10-secreting regulatory T cells in asthmatic children [J] . WANG Wei, XIANG Li, LIU Yong-ge, 中华医学杂志（英文版） . 2010,第015期
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4. Induction of Th1-Type Immune Response by Chitosan Nanoparticles Containing Plasmid DNA Encoding House Dust Mite Allergen Der p 2 for Oral Vaccination in Mice [J] . Guoping Li, Zhigang Liu, Bin Liao, 中国免疫学杂志（英文版） . 2009,第001期
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机译：室内尘螨片和日本雪松花粉片双重舌下免疫疗法的安全性和免疫应答
6. Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet [J] . Gotoh Minoru, Okubo Kimihiro, Yuta Atsushi, Allergology international: official journal of the Japanese Society of Allergology . 2020,第1期

机译：双舌下免疫疗法与日本雪松花粉片的安全剖面与免疫响应
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机译：过敏原特异性免疫疗法诱导的功能性IgE阻断因子与IgG4抗体和屋尘螨过敏儿童的症状减轻相关（第169卷，第113页，2016）
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机译：房屋尘螨过敏的新型免疫疗法策略
9. Structural, Functional and Immunological Studies of Group 1 and 2 House Dust Mite and Profilin Allergens for the Development of Allergen Specific Diagnostics and Immunotherapy [D] . Kapingidza, Anyway B. 2020

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10. Serum Soluble ST2 Correlated with Symptom Severity and Clinical Response of Sublingual Immunotherapy for House Dust Mite-Induced Allergic Rhinitis Patients [O] . Kang Zhu, Cui Xia, Jingguo Chen, 2021

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11. Efficacy and safety of the SQ house dust mite sublingual immunotherapy tablet in Japanese adults and adolescents with house dust mite–induced allergic rhinitis [O] . Kimihiro Okubo, Keisuke Masuyama, Toru Imai, 2017

机译：日本成年人和青少年SQ House粉尘舌下螨虫的功效和安全性与房屋粉尘诱发过敏性鼻炎的青少年
12. Mite Antigen Concentrations in House Dust and the Occurrence of Wheezing in Children with Dust Mite Allergy [R] . Henderson, F. W., Lindstrom, A. B., Beck, M. A., 1993

机译：尘螨过敏儿童房尘中的螨抗原浓度与喘息的发生

Decrease in CD38(+) TH2A cell frequencies following immunotherapy with house dust mite tablet correlates with humoral responses

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