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首页> 外文期刊>Colloid and polymer science >Investigation of the nano-hydroxyapatite with different surface modifications on the properties of poly(lactide-co-glycolide acid)/poly(trimethylene carbonate)/nano-hydroxyapatite composites
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Investigation of the nano-hydroxyapatite with different surface modifications on the properties of poly(lactide-co-glycolide acid)/poly(trimethylene carbonate)/nano-hydroxyapatite composites

机译：不同表面修饰对聚（丙交酯 - 共乙酸乙酸）/聚（三甲基碳酸酯）/纳米羟基磷灰石复合材料性能的纳米羟基磷灰石

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摘要

Nano-hydroxyapatite (HA) was successfully treated by three different surface modification methods of oleic acid (OA), silane coupling agent gamma-aminopropyl triethoxysilane (KH550), and ethenyltrimethoxysilane (YDH171), respectively. Then, the treated HA and unmodified HA with 8 wt% were introduced into PLGA/PTMC blends, respectively. And the fracture morphology, thermal property, crystallization behavior, mechanical properties, surface wettability, and in vitro bioactivity of PLGA/PTMC/HA ternary composites were investigated. The results showed that the PLGA/PTMC/HA composite with the HA surface modified by OA had the highest mechanical properties, while the PLGA/PTMC/HA composite with the HA treated by silane coupling agent YDH171 had the excellent toughness, compared to the other samples. Moreover, the cells' proliferation results confirmed that the ternary composites exhibited better biocompatibility. All the results suggested that the surface modification of HA was an ideal method in this study, and they would be potential to be used in the field of bone repair in the future.
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