Early age at start of antiretroviral therapy associated with better virologic control after initial suppression in HIV-infected infants

Shiau Stephanie; Strehlau Renate; Technau Karl-Gunter; Patel Faeezah; Arpadi Stephen M.; Coovadia Ashraf; Abrams Elaine J.; Kuhn Louise

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Early age at start of antiretroviral therapy associated with better virologic control after initial suppression in HIV-infected infants

机译：在艾滋病毒感染婴儿初始抑制后与更好的病毒学对照相关的抗逆转录病毒治疗开始时的早期

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Objective: The report of the 'Mississippi baby' who was initiated on antiretroviral therapy (ART) within 30 h of birth and maintained viral suppression off ART for 27 months has increased interest in the timing of ART initiation early in life. We examined associations between age at ART initiation and virologic outcomes in five cohorts of HIV-infected infants and young children who initiated ART before 2 years of age in Johannesburg, South Africa.

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来源
《AIDS》 |2017年第3期|共10页
作者
Shiau Stephanie; Strehlau Renate; Technau Karl-Gunter; Patel Faeezah; Arpadi Stephen M.; Coovadia Ashraf; Abrams Elaine J.; Kuhn Louise;
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作者单位

Columbia Univ Coll Phys &

Surg Gertrude H Sergievsky Ctr New York NY USA;

Univ Witwatersrand Rahima Moosa Mother &

Child Hosp Empilweni Serv &

Res Unit Fac Hlth Sci Dept;

Univ Witwatersrand Rahima Moosa Mother &

Child Hosp Empilweni Serv &

Res Unit Fac Hlth Sci Dept;

Univ Witwatersrand Rahima Moosa Mother &

Child Hosp Empilweni Serv &

Res Unit Fac Hlth Sci Dept;

Columbia Univ Coll Phys &

Surg Gertrude H Sergievsky Ctr New York NY USA;

Univ Witwatersrand Rahima Moosa Mother &

Child Hosp Empilweni Serv &

Res Unit Fac Hlth Sci Dept;

Columbia Univ Mailman Sch Publ Hlth Dept Epidemiol New York NY USA;

Columbia Univ Coll Phys &

Surg Gertrude H Sergievsky Ctr New York NY USA;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
antiretroviral therapy; early treatment; infant; viral suppression; virologic control;

机译：抗逆转录病毒治疗;早期治疗;婴儿;病毒抑制;病毒学控制;

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专利

1. Adherence level to antiretroviral therapy predict the time to viral load suppression of adult people living with HIV on antiretroviral therapy in Arba Minch general hospital [J] . Sultan Hussen, Mohammedaman Mama, Bitewu Mekonnen, 中华医学杂志（英文版） . 2019,第023期
2. An Assessment of the Level of Knowledge of HIV-Infected Patients about Highly Active Antireteroviral Therapy and Waiting Times and Their Influence on Antiretroviral Therapy Adherence at a Primary Healthcare Centre of South Africa [J] . N L Katende-Kyenda 药剂与药理学：英文版 . 2017,第007期
3. Early age at start of antiretroviral therapy associated with better virologic control after initial suppression in HIV-infected infants [J] . Shiau Stephanie, Strehlau Renate, Technau Karl-Gunter, AIDS . 2017,第3期

机译：在艾滋病毒感染婴儿初始抑制后与更好的病毒学对照相关的抗逆转录病毒治疗开始时的早期
4. Virologic Suppression in Nevirapine-Exposed HIV-Infected Infants Initiating Antiretroviral Therapy in Rural Uganda [J] . Jenna Kay1 Humphrey Wanzira2 Taylor Sandison3 Abel Kakuru2 Victor Bigira2 Moses Kamya24 Jaco Homsy5 Jordan W. Tappero6 Diane Havlir1 Grant Dorsey1 and Theodore Ruel7 Journal of Tropical Pediatrics . 2012,第3期

机译：在乌干达农村地区开展抗逆转录病毒治疗的奈韦拉平暴露于艾滋病毒感染的婴儿中的病毒学抑制。
5. Virologic suppression in nevirapine-exposed HIV-infected infants initiating antiretroviral therapy in rural Uganda [J] . KayJ., WanziraH., SandisonT., Journal of tropical pediatrics. . 2012,第3期

机译：在乌干达农村地区开展抗逆转录病毒治疗的纳韦拉平暴露于艾滋病毒感染婴儿的病毒学抑制
6. Effect of highly active antiretroviral therapy (HAART) on lipid abnormalities in HIV-infected patients [C] . Estari Mamidala 2011 international conference on medical information and bioengineering. . 2011

机译：高效抗逆转录病毒疗法（HAART）对HIV感染患者血脂异常的影响
7. Antiretroviral regimen central nervous penetration, viral control, and age of attainment of developmental milestones in early treated HIV-infected infants. [D] . Crowell, Claudia S. 2015

机译：抗逆转录病毒疗法的中枢神经渗透，病毒控制和达到早期里程碑的HIV感染婴儿的发展里程碑年龄。
8. Early age at start of antiretroviral therapy associated with better virologic control after initial suppression in HIV-infected infants [O] . Stephanie Shiau, Renate Strehlau, Karl-Günter Technau, -1

机译：在最初被抑制后HIV感染婴儿的抗逆转录病毒疗法开始时年龄较早并具有更好的病毒学控制
9. Virologic Suppression in Nevirapine-Exposed HIV-Infected Infants Initiating Antiretroviral Therapy in Rural Uganda [O] . J. Kay, H. Wanzira, T. Sandison, 2011

机译：在乌干达农村发起尿道暴露的艾滋病毒感染婴儿的病毒学抑制
10. Cumulative Viral Load and Virologic Decay Patterns after Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS [R] . Marconi, V. C., Grandits, G., Okulicz, J. F., 2011

机译：艾滋病病毒感染者抗逆转录病毒治疗后的累积病毒载量和病毒学衰变模式影响CD4恢复和艾滋病

Early age at start of antiretroviral therapy associated with better virologic control after initial suppression in HIV-infected infants

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