首页> 外文期刊>AIDS & hepatitis digest >The Cost-Effectiveness Of Testing for Ns5a Resistance-Associated Polymorphisms at Baseline in Genotype I A-Infected (Treatment-Naive and Treatment-Experienced) Subjects Treated with All-Oral Elbasvir/ Grazoprevir Regimens in the United States
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The Cost-Effectiveness Of Testing for Ns5a Resistance-Associated Polymorphisms at Baseline in Genotype I A-Infected (Treatment-Naive and Treatment-Experienced) Subjects Treated with All-Oral Elbasvir/ Grazoprevir Regimens in the United States

机译:在基因型中对基线的NS5A抗性相关多态性测试的成本效益Ia感染(治疗 - 幼稚和治疗经验丰富的)受试者在美国治疗的全口头埃尔巴斯韦/ Grazophir方案治疗

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摘要

This study showed that resistance-as-sociated variants (RAVs) testing-based strategy is superior to ombitasvir/ paritaprevir/ritonavir+dasabuvir (3D)+ ribavirin (RBV) or 8 weeks of ledi-pasvir/sofosbuvir (LDV/SOF) and is cost-effective compared with elbasvir/ grazoprevir (EBR/GZR) without testing. This conclusion is robust in several sensitivity analyses
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