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首页> 外文期刊>Anaesthesia: Journal of the Association of Anaesthetists of Great Britain and Ireland >Heparinase-modified thromboelastography can result in a fibrinolytic pattern.
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Heparinase-modified thromboelastography can result in a fibrinolytic pattern.

机译：肝素改性的血栓球运动可以导致纤维蛋白溶解图案。

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摘要

Thromboelastography (TEG) is used in the diagnosis and management of coagulation disorders in a number of clinical specialties, including intensive care medicine.Heparin used to prevent obstruction of blood-sampling catheters with blood clots may interfere with the results of TEG [1-3], and the use of heparinase-coated cuvettes has been recommended to reverse this effect [4].When performing TEG in patients with severe sepsis, we noticed that someblood samples pre-treated with hepa-rinase showed decreasing clot amplitude resembling a fibrinolytic pattern (Fig. 6). This could have been due to true fibrinolysis or to disconnection of the undissolved clot from the pin or the cuvette during platelet-mediated clot retraction [5]. We felt that true fibrinolysis was unlikely, as none of our patients with a fibrinolytic TEG pattern had bleeding problems clinically or were receiving anticoagulant therapy. Moreover, inspection of the clot did not reveal signs of fibrinolysis and we detected visible disconnection of the clot from the pin or the cuvette.
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