• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of biomedical nanoscience and nanotechnology >Histopathological and biochemical correlation of antidiabetic activity of zinc oxide nanoparticles after oral administration in Wistar rats
【24h】

Histopathological and biochemical correlation of antidiabetic activity of zinc oxide nanoparticles after oral administration in Wistar rats

机译：氧化锌纳米颗粒在Wistar大鼠口服施用后氧化锌纳米颗粒的组织病理学和生化相关性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Nanomaterials have high surface-to-volume ratios and possess unique physiological and biochemical properties modulating a wide range of reactions causing inflammation and cell toxicity. The present work was aimed to evaluate histopathological and biochemical changes in organs of the glucose metabolism after treatment with zinc oxide nanoparticles (ZnONP) in diabetic Wistar rats. Induction of diabetes was done with Streptozotocine and animals were treated with ZnONP in three graded doses in different groups. Glipizide was added in standard treatment and one of the ZnONP groups. Overall histopathological changes were observed as mild to moderate in diabetic animals that received no treatment and minimal in those that received standard treatment as Glipizide. The animals that received ZnONP as a treatment showed minimal to no abnormality detected on histopathology. Biochemical analysis revealed that ZnONP possess antidiabetic and lipid lowering activity which was consistent with histopathology. It is concluded that ZnONP play pivotal role in glucose metabolism and should be investigated further so that they can be introduced into diabetes treatment.
机译：None

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号