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首页> 外文期刊>European Journal of Obstetrics, Gynecology and Reproductive Biology: An International Journal >Influence of age on treatment and prognosis of invasive cervical cancer
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Influence of age on treatment and prognosis of invasive cervical cancer

机译：年龄对侵袭性宫颈癌治疗和预后的影响

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Objective: Invasive cervical cancer is considered a young women's disease, however up to 20 % of cases develop cervical cancer at advanced ages. The aim was to characterize invasive cervical cancer in women aged 65 and older assessing age-specific survival differences. Study design: A retrospective study including cervical cancer patients was conducted at Hospital del Mar Barcelona from July-20 07 to December-2016. Women were stratified: 65years. Clinical and pathological data were collected. Multivariate analysis was used to compare outcomes. Adjusted hazard ratios with 95 % confidence intervals for disease-free survival, and overall survival were estimated using Cox proportional hazards models. Results: 124 patients with invasive cervical cancer (n = 87 65years) were included. At diagnosis, 48.3 % of 65years (p = 0.018). Standard treatment was given to 83.9 % of patients in 65years (p = 0.015). Disease-free survival and overall survival showed no significant differences between groups. Age >65 did not predict worse disease-free survival (HR: 0.3 95 %CI, 0.04-3.1, p = 0.347) or overall survival (HR: 0.82 95 %CI, 0.3-2.3, p = 0.729). Conclusion: Invasive cervical cancer was diagnosed at advanced stages and was treated less frequently with radical intention in patients >65years; overall survival and disease-free survival were similar to those cervical cancer diagnosed at younger ages. (c) 2021 Elsevier B.V. All rights reserved.
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