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首页> 外文期刊>Marine genomics >Strand-specific RNA-Seq analysis provides first insight into transcriptome response of & IT;Vibrio alginolyticus & IT; to phage infection
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Strand-specific RNA-Seq analysis provides first insight into transcriptome response of & IT;Vibrio alginolyticus & IT; to phage infection

机译：STRAND特异性RNA-SEQ分析提供了对＆IT的转录组响应的首先见解; vibrio alginyticus＆IT; 噬菌体感染

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摘要

RNA-Seq transcriptome analysis of bacteria during phage infection has been occasionally reported in last several years but little is known about how Vibrio bacteria respond to phage invasion on global transcriptome level. In the present study, transcriptome profiling of V. alginolyticus during a lytic phage infection was first investigated through strand-specific RNA-Seq analysis. The results revealed that 346 unigenes were up-regulated and 860 unigenes were down-regulated during the infection of phage Vp670. Notably, the unigenes involving in phosphorelay signal transduction system were largely down-regulated in infected V. alginolyticus cells. However, some unigenes in the GO terms (DNA binding and sequence-specific DNA binding transcription factor activity) were up-regulated including a csp gene coding cold shock protein. These transcriptome data contribute to a more comprehensive insight into cellular response of V. alginolyticus to phage infection and help us deeply understand the phage-host interplay on molecular levels. (C) 2017 Elsevier B.V. All rights reserved.
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  • 来源
    《Marine genomics》 |2018年第2018期|共4页
  • 作者

    Luo Peng; Liu Qiuting; Deng Yiqin; Tian Yushun; Yun Long; Hu Chaoqun;

  • 作者单位

    Chinese Acad Sci South China Sea Inst Oceanol Guangdong Prov Key Lab Appl Marine Biol CAS Key Lab Trop Marine Bioresources &

    Ecol Guangzhou 510301 Guangdong Peoples R China;

    Chinese Acad Sci South China Sea Inst Oceanol Guangdong Prov Key Lab Appl Marine Biol CAS Key Lab Trop Marine Bioresources &

    Ecol Guangzhou 510301 Guangdong Peoples R China;

    Chinese Acad Sci South China Sea Inst Oceanol Guangdong Prov Key Lab Appl Marine Biol CAS Key Lab Trop Marine Bioresources &

    Ecol Guangzhou 510301 Guangdong Peoples R China;

    Chinese Acad Sci South China Sea Inst Oceanol Guangdong Prov Key Lab Appl Marine Biol CAS Key Lab Trop Marine Bioresources &

    Ecol Guangzhou 510301 Guangdong Peoples R China;

    Chinese Acad Sci South China Sea Inst Oceanol Guangdong Prov Key Lab Appl Marine Biol CAS Key Lab Trop Marine Bioresources &

    Ecol Guangzhou 510301 Guangdong Peoples R China;

    Chinese Acad Sci South China Sea Inst Oceanol Guangdong Prov Key Lab Appl Marine Biol CAS Key Lab Trop Marine Bioresources &

    Ecol Guangzhou 510301 Guangdong Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 遗传学;
  • 关键词

    Transcriptome; Vibrio alginolyticus; Phage infection; Differential expression genes;

    机译：转录组;vibrio alginolyticus;噬菌体感染;差异表达基因;

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