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首页> 外文期刊>Monographs in clinical cytology. >Non-Hodgkin Lymphoma
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Non-Hodgkin Lymphoma

机译：非霍奇金淋巴瘤

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The last WHO classification [1] still divides non-Hodgkin lymphoma (NHL) into B-cell type, which accounts for about 90% of cases, T-cell type (about 10%), and a very small number of "null-cell" type. According to morphology and cell size, NHL may be basically distinguished as small-cell NHL or medium/large-cell NHL, and this broad subdivision is reliable at fine-needle cytology (FNC) as well. According to the cell size criterion, the most common small-cell NHL are generally monomorphous entities: small lymphocytic lympho-ma/chronic lymphocytic leukaemia (SLL/CLL), mantle cell lymphoma (MCL), marginal zone lymphoma (MZL), follic-ular lymphoma (FL) grades I and II, and lymphoplasmacytic lymphoma (LpcL). This group almost exclusively includes B-cell NHL and natural killer lymphoma. The medium-to-large group is more polymorphous and heterogeneous, and includes diffuse large B-cell lymphoma (DLBCL), FL grade III, Burkitt and Burkitt-like lymphoma (BL and BL-like), precursor B-and T-cell lymphoma (LL-T), peripheral T-cell lymphoma not otherwise specified (PTCL NOS), and ana-plastic large-cell lymphoma (ALGL). Whereas cytological features may suggest a specific entity, morphology alone cannot identify the definite phenotype of each NHL, which needs to be assessed by appropriate immunocytochemistry (ICC) or flow cytometry (FC) phenotypization.
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