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Fine-Needle Cytology: Technical Procedures and Ancillary Techniques

机译:细针细胞学:技术程序和辅助技术

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Preliminary Aspects: Despite the efforts towards automated diagnostic procedures, fine-needle cytology (FNC), with or without aspiration, smearing, rapid on-site evaluation (ROSE), and material management remain operator-dependent procedures that require manual and professional skills. Much of the efficacy of the method and of ancillary techniques depends on the correctness of the initial procedures. Conversely, FNC non-effectiveness and many diagnostic mistakes are caused by inadequate or inaccurate FNC. Therefore, perfect sampling, smearing, staining, ROSE, and a proper management of the diagnostic material are key points to achieve an adequate and effective lymph node (LN)-FNC. In some institutions, FNC is performed by clinicians, while cytopatholo-gists are required to evaluate and diagnose smears. However, the authors believe that LN-FNC should be performed by the cytopathologists themselves in order to optimize the procedures, as is described below. A preliminary evaluation of clinical, serological, and imaging data is required, possibly in the presence of patients. Routine laboratory data including prothrombin time, partial thromboplastin time, and platelet count should be checked before FNC, with severe coagulation disorders representing contraindications.
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