Multitarget neuroprotection by quercetin: Changes in gene expression in two perinatal asphyxia models

Cardozo V.; Vaamonde L.; Parodi-Talice A.; Zuluaga M. J.; Agrati D.; Portela M.; Lima A.; Blasina F.; Dajas F.; Bedo G.

首页> 外文期刊>Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry >Multitarget neuroprotection by quercetin: Changes in gene expression in two perinatal asphyxia models

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Multitarget neuroprotection by quercetin: Changes in gene expression in two perinatal asphyxia models

机译：槲皮素的多元神经保护作用：两种围产期窒息模型中基因表达的变化

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Hypoxic-ischemic encephalopathy (HIE) causes mortality and long-term neurologic morbidities in newborns, affecting pathways related to energy failure, excitotoxicity and oxidative stress that often lead to cell death. The whole process of HIE injury is coupled to changes in the expression of a great array of proteins. A nanoliposomal preparation of the flavonoid quercetin has been shown to exert neuroprotective effects in perinatal asphyxia models.

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来源
《Neurochemistry International: The International Journal for the Rapid Publication of Critical Reviews, Preliminary and Original Research Communications in Neurochemistry》 |2021年第1期|共14页
作者
Cardozo V.; Vaamonde L.; Parodi-Talice A.; Zuluaga M. J.; Agrati D.; Portela M.; Lima A.; Blasina F.; Dajas F.; Bedo G.;
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作者单位

Univ Republ Udelar Fac Ciencias Secc Genet Evolut Montevideo Uruguay;

Univ Republ Udelar Fac Med Dept Neonatol Montevideo Uruguay;

Univ Republ Udelar Fac Ciencias Secc Genet Evolut Montevideo Uruguay;

Univ Republ Udelar Secc Fisiol &

Nutr Fac Ciencias Montevideo Uruguay;

Univ Republ Udelar Secc Fisiol &

Nutr Fac Ciencias Montevideo Uruguay;

Inst Pasteur Montevideo Unidad Bioquim &

Proteom Analit Montevideo Uruguay;

Inst Pasteur Montevideo Unidad Bioquim &

Proteom Analit Montevideo Uruguay;

Univ Republ Udelar Fac Med Dept Neonatol Montevideo Uruguay;

Minist Educ &

Cultura Inst Invest Biol Clemente Estable Dept Neuroquim Montevideo Uruguay;

Univ Republ Udelar Fac Ciencias Secc Genet Evolut Montevideo Uruguay;

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原文格式 PDF
正文语种 eng
中图分类生物化学;
关键词
Perinatal asphyxia; Neuroprotection; Quercetin; Proteomics;

机译：围产期窒息;神经保护;槲皮素;蛋白质组学;

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专利

1. Gene2DGE： A Perl Package for Gene Model Renewal with Digital Gene Expression Data [J] . Xiaoli Tang, Libin Deng, Dake Zhang, 基因组蛋白质组与生物信息学报：英文版 . 2012,第001期
2. Gene2DGE: A Perl Package for Gene Model Renewal with Digital Gene Expression Data [J] . Xiaoli Tang, Libin Deng, Dake Zhang, 基因组蛋白质组与生物信息学报（英文版） . 2012,第001期
3. An Accurate Model for the Expression of the Antisense RNA Block Gene：the Firefly Luciferase Gene—Xenopus Oocyte System [J] . 金振华, 裴文, 等发育与生殖生物学报：英文版 . 1992,第001期
4. Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model [J] . Robertson Nicola J., Faulkner Stuart, Fleiss Bobbi, Brain: A journal of neurology . 2013,第1期

机译：褪黑素增强围产期窒息模型的低温神经保护
5. Quercetin Glycosides Induced Neuroprotection by Changes in the Gene Expression in a Cellular Model of Parkinson's Disease [J] . Magalingam Kasthuri Bai, Radhakrishnan Ammu, Ramdas Premdass, Journal of Molecular Neuroscience: MN . 2015,第3期

机译：槲皮素糖苷通过帕金森氏病细胞模型中基因表达的变化诱导神经保护作用
6. Perinatal Asphyxia in Rat Alters Expression of Novel Schizophrenia Risk Genes [J] . Alessandra Paparelli, Keiko Iwata, Tomoyasu Wakuda, Frontiers in Molecular Neuroscience . 2017,第10期

机译：大鼠围产期窒息改变新型精神分裂症风险基因的表达
7. Dietary composition influences the impacts of BDE-47 on tissue accumulation, cerebral gene expression and reflex development in perinatally-exposed mice pups [C] . Haave Marte, Folven Kristin Ingvaldsen, Glover Chris Neill, International symposium on halogenated persistent organic pollutants . 2009

机译：饮食成分会影响BDE-47对围生期暴露的幼仔组织积累，脑基因表达和反射发育的影响
8. Some consequences for social behavior of perinatal asphyxia and csection delivery of full term male rats. [D] . Varholick, Justin A. 2014

机译：足月雄鼠围生期窒息和剖腹产对社会行为的某些影响。
9. Cerebellar Cytokine Expression in a Rat Model for Fetal Asphyctic Preconditioning and Perinatal Asphyxia [O] . Evi Vlassaks, Tomasz Brudek, Bente Pakkenberg, -1

机译：小脑细胞因子在胎儿窒息预处理和围产期窒息模型中的表达
10. Quercetin glycosides induced neuroprotection by changes in the gene expression in a cellular model of Parkinson's disease [O] . Magalingam, Kasthuri Bai, Radhakrishnan, Ammu, Ramdas, Premdass, 2015

机译：槲皮素苷通过帕金森氏病细胞模型中基因表达的变化诱导神经保护
11. Neuroprotection by Progesterone Through Simulation of Mitochondrial Gene Expression. [R] . Fiskum, G. 2002

机译：黄体酮对线粒体基因表达的神经保护作用。

Multitarget neuroprotection by quercetin: Changes in gene expression in two perinatal asphyxia models

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