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首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >Localized crystal‐storing histiocytosis of the posterior fossa
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Localized crystal‐storing histiocytosis of the posterior fossa

机译：后窝的局部晶体储存组织织菌

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摘要

Crystal‐storing histiocytosis (CSH) is an uncommon histiocytic proliferation reported to involve diverse organs and tissues, but involvement of the central nervous system (CNS) is rare. In most cases CSH is identified in association with underlying lymphoproliferative, plasma cell diseases or rarely with various inflammatory or infectious conditions. CSH is characterized by the cytoplasmic accumulation of crystalline material in histiocytes, most commonly of kappa immunoglobulin light chain. We report a unique case of localized CSH involving the left cerebellum and caudal brain stem in a young man with a history of gout but without known lymphoproliferative or plasma cell disorders. Awareness of this entity is important diagnostically, but also to ensure appropriate management and follow‐up, particularly in the absence of apparent underlying malignancy.
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