Illuminating new structures of a rod CNG channel: The eye's chemoelectrical converter

Evans Eric G. B.; Zagotta William N.

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Illuminating new structures of a rod CNG channel: The eye's chemoelectrical converter

机译：照亮棒CNG通道的新结构：眼睛的斡旋式转换器

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In this issue of Neuron, Xue et al. report high-resolution structures of the human cGMP-activated ion channel CNGA1 from rod photoreceptors. These structures provide valuable insights into the processes of cGMP-dependent activation and Ca2+ block and permeation.

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《Neuron》 |2021年第8期|共4页
作者
Evans Eric G. B.; Zagotta William N.;
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Univ Washington Dept Physiol &

Biophys Seattle WA 98195 USA;

Univ Washington Dept Physiol &

Biophys Seattle WA 98195 USA;

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正文语种 eng
中图分类神经病学;
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2. Highlights for the 6th International Ion Channel Conference: ion channel structure, function,disease and therapeutics [J] . Limei Wang, Kewei Wang 药学学报（英文版） . 2017,第006期
3. Direct blockade of both cloned rat rod photoreceptor cyclic nucleotide-gated non-selective cation (CNG) channel alpha-subunit and native CNG channels from Xenopus rod outer segments by H-8, a non-specific cyclic nucleotide-dependent protein kinase in [J] . Wei JY, Cohen ED, Barnstable CJ Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 1997,第1期

机译：H-8是非特异性环状核苷酸依赖性蛋白激酶H-8，可直接阻断非洲爪蟾杆外部片段对大鼠杆状光感受器环状核苷酸门控非选择性阳离子（CNG）通道α亚基和天然CNG通道的直接阻断
4. Functional Role of hCNGB3 in Regulation of Human Cone CNG Channel: Effect of Rod Monochromacy-Associated Mutations in hCNGB3 on Channel Function. [J] . Okada A, Ueyama H, Toyoda F, Investigative ophthalmology & visual science . 2004,第7期

机译：hCNGB3在调节人锥CNG通道中的功能作用：hCNGB3中杆单色性相关突变对通道功能的影响。
5. Studying ligand binding and gating of rod CNG channels by FRET [J] . Groeneveld K., Melle C., Biskup C., Acta physiologica . 2019,第S719期

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6. Thermoelectrical and Chemoelectrical Properties of Conductive Polymer NanoComposites (CPC): Different Strategies for Conducting Network Structuring [C] . Jean-FranÁois FELLER, Karim ZRIBI, Guillaume DROVAL MRS spring meeting . 2007

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7. cis- and trans-regulatory mechanisms of CNG channel targeting and localization in C. elegans. [D] . Wojtyniak, Martin. 2013

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8. Calmodulin controls the rod photoreceptor CNG channel through an unconventional binding site in the N-terminus of the beta-subunit. [O] . D Weitz, M Zoche, F Müller, 1998

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10. Rod-Cone Interaction in the Dark-Adapted Eye [R] . 1956

机译：黑暗适应眼中的棒 - 锥相互作用

Illuminating new structures of a rod CNG channel: The eye's chemoelectrical converter

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