Association of-819 T/C IL-10 gene promoter polymorphisms with susceptibility to leprosy in South Sumatera Indonesia

Oktariana Desi; Argentina Fifa; Hafy Zen; Salim Eddy M.; Kurniati Nova; Rahadiyanto Kemas Yakub; Lusiana Evi

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Association of-819 T/C IL-10 gene promoter polymorphisms with susceptibility to leprosy in South Sumatera Indonesia

机译：-819T / C IL-10基因启动子多态性与南泉省印度尼西亚的麻风病易感性

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Background: The prevalence of leprosy continues to increase, especially in Indonesia, which is one of the endemic areas of leprosy. One cytokine that plays an important role in the pathogenesis of leprosy is IL-10. Mutations in the gene could cause changes in IL-10 gene expression. One of the most common polymorphisms associated with the IL-10 gene is -819 C/T polymorphism, which is could affect the production of IL-10, and thus influence the process of microbial elimination in the development of leprosy.

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来源
《Leprosy review》 |2021年第2期|共8页
作者
Oktariana Desi; Argentina Fifa; Hafy Zen; Salim Eddy M.; Kurniati Nova; Rahadiyanto Kemas Yakub; Lusiana Evi;
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作者单位

Univ Sriwijaya Med Fac Clin Pathol Dept Palembang Indonesia;

Univ Sriwijaya Med Fac Dermatovenereol Dept Palembang Indonesia;

Univ Sriwijaya Med Fac Biomed Dept Palembang Indonesia;

Univ Sriwijaya Med Fac Internal Med Dept Palembang Indonesia;

Univ Sriwijaya Med Fac Internal Med Dept Palembang Indonesia;

Univ Sriwijaya Med Fac Clin Pathol Dept Palembang Indonesia;

Univ Sriwijaya Med Fac Pharmacol Dept Palembang Indonesia;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学与性病学;
关键词
Leprosy; interleukin-10; polymorphism;

机译：麻风素;白细胞介素-10;多态性;

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Association of-819 T/C IL-10 gene promoter polymorphisms with susceptibility to leprosy in South Sumatera Indonesia

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