Platelets and viruses

Antoniak Silvio; Mackman Nigel

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Platelets and viruses

机译：血小板和病毒

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Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns. Platelets can be beneficial and/or detrimental during viral infections. They reduce blood-borne viruses by engulfing the free virus and presenting the virus to neutrophils. However, platelets can also enhance inflammation and tissue injury during viral infections. Here, we discuss the roles of platelets in viral infection.

机译：血小板在损伤后维持血管完整性中起着至关重要的作用。此外，血小板有助于对病原体的免疫反应。例如，它们表达介导病毒结合的受体，以及激活细胞以响应病原体相关分子模式的toll样受体。在病毒感染期间，血小板可能有益和/或有害。它们通过吞噬游离病毒并将病毒呈递给中性粒细胞来减少血液传播的病毒。然而，在病毒感染期间，血小板也会增强炎症和组织损伤。在这里，我们讨论血小板在病毒感染中的作用。

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来源
《Platelets》 |2021年第3期|共6页
作者
Antoniak Silvio; Mackman Nigel;
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作者单位

Univ N Carolina Dept Med UNC Blood Res Ctr Chapel Hill NC 27599 USA;

Univ N Carolina Dept Med UNC Blood Res Ctr Chapel Hill NC 27599 USA;

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原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
Platelets; myocarditis; influenza A virus; coronavirus;

机译：血小板;心肌炎;流感病毒;冠状病毒;

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专利

1. A duplex RT-PCR assay for detection of H9 subtype avian influenza viruses and infectious bronchitis viruses [J] . WEI Yan-di, GAO Wei-hua, SUN Hong-lei, 农业科学学报（英文版） . 2016,第009期
2. A duplex RT-PCR assay for detection of H9 subtype avian influenza viruses and infectious bronchitis viruses [J] . WEI Yan-di, GAO Wei-hua, SUN Hong-lei, 农业科学学报：英文版 . 2016,第009期
3. Residual platelet reactivity is preferred over platelet inhibition rate in monitoring antiplatelet efficacy: insights using thrombelastography [J] . Hong-yi Wu, Chi Zhang, Xin Zhao, 中国药理学报：英文版 . 2020,第002期
4. Inactivation of a broad spectrum of viruses and parasites by photochemical treatment of plasma and platelets using amotosalen and ultraviolet A light [J] . Transfusion: The Journal of the American Association of Blood Banks . 2020,第6期

机译：使用amotosalen和紫外线光化处理通过光化学处理来灭活广谱的病毒和寄生虫
5. Inactivation of three emerging viruses - severe acute respiratory syndrome coronavirus, Crimean-Congo haemorrhagic fever virus and Nipah virus - in platelet concentrates by ultraviolet C light and in plasma by methylene blue plus visible light [J] . Eickmann Markus, Gravemann Ute, Handke Wiebke, Vox Sanguinis: International Journal of Blood Transfusion and Immunohaematology . 2020,第3期

机译：三种新兴病毒 - 严重急性呼吸综合征冠状病毒，克里米亚 - 刚果出血热病毒和NIPAH病毒 - 亚甲基蓝加可见光的血小板浓缩物
6. Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis viruses [J] . Amrita Ojha, Angika Bhasym, Sriparna Mukherjee, EBioMedicine . 2019,第3期

机译：血小板因子4促进登革热和日本脑炎病毒的快速复制和繁殖
7. Proteomic Analysis of the Platelet Membrane and Platelet Releasate: Insights into the Interaction of Platelets with other Blood Cells [C] . Geraldine M. Walsh, Daniel Ramb, Juergen Kast American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：血小板膜和血小板的蛋白质组学分析释放：血小板与其他血细胞相互作用的见解
8. In Vitro Platelet Production: Promoting Megakaryocyte Terminal Differentiation, Demonstrating Platelet Functionality, and Developing an Automated Process for Platelet Harvest. [D] . Schlinker, Alaina C. 2014

机译：体外血小板生产：促进巨核细胞末端分化，展示血小板功能并开发血小板收获的自动化过程。
9. Interaction between human blood platelets viruses and antibodies. IV. Post-Rubella thrombocytopenic purpura and platelet aggregation by Rubella antigen–antibody interaction [O] . G. Myllylä, A. Vaheri, T. Vesikari, 1969

机译：人血小板病毒和抗体之间的相互作用。 IV。风疹抗原-抗体相互作用后的风疹后血小板减少性紫癜和血小板聚集
10. Interaction between Viruses and Platelets: Requirement of Haemolytic Activity for Platelet Aggregation Induced by Paramyxoviruses [O] . M. A. Chernesky, R. P. B. Larke, A. G. G. Turp Ie 2014

机译：病毒与血小板的相互作用：副粘病毒诱导血小板聚集的溶血活性要求
11. Mean Platelet Volume and Platelet Immunofluorescence as Indicators of Platelet Compatibility [R] . Melaragno, A. J., Hall, S., Immerman, K., 1983

机译：平均血小板体积和血小板免疫荧光作为血小板相容性的指标

Platelets and viruses

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