Graves' disease in adults Antithyroid drugs, radioactive iodine, or sometimes thyroidectomy

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Graves' disease in adults Antithyroid drugs, radioactive iodine, or sometimes thyroidectomy

机译：在成人抗胆汁药物，放射性碘，或有时甲状腺切除术中的坟墓疾病

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What is the best treatment for adults with Graves' disease in 2016? To answer this question, we reviewed the literature using the standard Prescrire methodology. When the symptoms of hyperthyroidism are poorly tolerated, a beta-blocker relieves tachycardia, anxiety and tremor. Three treatments have been shown to be effective in controlling hyperthyroidism: antithyroid drugs, radioiodine, and thyroidectomy. Carbimazole and its metabolite thiamazole are the antithyroid drugs with the best harm-benefit balance, except during the first trimester of pregnancy. About 50% of patients are cured after 12 to 18 months of treatment.

机译：2016年Graves病成人的最佳治疗方案是什么？为了回答这个问题，我们使用标准的Prescrire方法回顾了文献。当甲亢的症状耐受性差时，β受体阻滞剂可以缓解心动过速、焦虑和震颤。三种治疗方法已被证明能有效控制甲亢：抗甲状腺药物、放射性碘和甲状腺切除术。卡比咪唑及其代谢物噻唑是抗甲状腺药物，除了在怀孕的前三个月，它们的利弊平衡最好。大约50%的患者经过12到18个月的治疗后痊愈。

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《Prescrire international》 |2017年第180期|共7页
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1. AN INVESTIGATION OF PEDIGREES OF 110 PATIENTS WITH GRAVES’ DISEASE AND THE CLINICAL SIGNIFICANCE OF DETERMINATIONS OF ANTITHYROID ANTIBODIES OF THEIR FIRST-DEGREE RELATIVES [J] . 王德全, 王洁贞, 任建民, 中华医学杂志：英文版 . 1994,第011期
2. Clinical analysis of radioactive iodine treatment in Grave’s hyperthyroidism patients with leucopenia [J] . 石丽红中国医学文摘：内科学分册（英文版） . 2013,第002期
3. Serum Thyroglobulin—A Sensitive Biomarker of Iodine Nutrition Status and Affected by Thyroid Abnormalities and Disease in Adult Populations [J] . DU Yang, GAO Yan Hui, FENG Zhuo Ying, 生物医学与环境科学（英文版） . 2017,第007期
4. Clinical study on the efficacy of iodine-131 in combined with Fufangjiakang tablets in the treatment of Graves’disease [J] . Min-Hong Pang, Zhi-Hong Lu 海南医科大学学报（英文版） . 2016,第012期
5. Outcomes of Graves’ Disease Patients Following Antithyroid Drugs, Radioactive Iodine, or Thyroidectomy as the First-line Treatment [J] . Xiaodong Liu, Carlos K. H. Wong, Wendy W. L. Chan, Annals of Surgery . 2021,第6期

机译：抗胆汁药物，放射性碘或甲状腺切除术后的甲虫病患者的结果为一线治疗
6. Comparison of long-term antithyroid drugs versus radioactive iodine or surgery for Graves' disease: A review of the literature [J] . El Kawkgi Omar M., Ross Douglas S., Stan Marius N. Clinical Endocrinology . 2021,第1期

机译：长期抗替代药物对放射性碘或手术的比较Graves疾病：文献综述
7. Impact of Lithium on Efficacy of Radioactive Iodine Therapy for Graves’ Disease: A Cohort Study on Cure Rate, Time to Cure, and Frequency of Increased Serum Thyroxine After Antithyroid Drug Withdrawal [J] . Fausto Bogazzi, Clara Giovannetti, Rezene Fessehatsion, The journal of clinical endocrinology and metabolism . 2010,第1期

机译：锂对放射性碘疗法对格雷夫斯病疗效的影响：一项关于抗甲状腺药停药后治愈率，治愈时间和血清甲状腺素升高频率的队列研究
8. Effects of radioactive iodine (~(131)I) on the thyroid of newborn, pubertal and adult rats [C] . Yumiko Nitt, Masaharu Hoshi, Kenji Kamiya International Symposium of Radiation and Homeostasis . 2002

机译：放射性碘（〜（131）I）对新生儿，青春期，成人大鼠甲状腺作用的影响
9. Development and application of novel detection methods for aqueous radioactive iodine. [D] . Grogan, Kelly Patrick. 2012

机译：新型放射性水碘检测方法的开发与应用。
10. Excessive Iodine Intake Does Not Increase the Recurrence Rate of Graves Disease after Withdrawal of the Antithyroid Drug in an Iodine-Replete Area [O] . Sun Mi Park, Yoon Young Cho, Ji Young Joung, 2015

机译：碘摄入过多地区服用抗甲状腺药后过量摄入碘不会增加Graves病的复发率
11. Quality of Life Is Worse at 6-10 Years after Radioactive Iodine Treatment of Graves’ Disease as Compared with Antithyroid Drugs or Surgery [O] . Sun Y. Lee 2019

机译：与抗胆汁药物或手术相比，在放射性碘治疗坟墓疾病的放射性碘治疗后6 - 10年的生活质量更严重
12. Approach to the Pediatric Patient with Graves' Disease: When Is Definitive Therapy Warranted [R] . Bauer, A. J. 2011

机译：对患有格雷夫斯病的儿科患者的方法：什么时候确定治疗是正确的

Graves' disease in adults Antithyroid drugs, radioactive iodine, or sometimes thyroidectomy

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