Fosfomycin trometamol during the first trimester of pregnancy: new data

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Fosfomycin trometamol during the first trimester of pregnancy: new data

机译：孕氟霉素Trometamol在怀孕的第一个三个月：新数据

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Lower urinary tract infections and asymptomatic bacteriuria are commonplace in pregnancy. In 2018, we concluded that during the first trimester of pregnancy, cefuroxime or possibly amoxicillin + clavulanic acid, were more prudent choices than fosfomycin trometamol and had similar efficacy (1). In 2019, new French data, based on about 5900 pregnant women from Haute-Garonne who were exposed to fosfomycin trometamol, including 2600 women exposed during the first trimester, did not demonstrate an increased risk of malformations with this drug (2). In practice, single-dose administration of fosfomycin trometamol is an option for lower urinary tract infection in a pregnant woman during the first trimester, as is cefuroxime or the combination of amoxicillin + clavulanic acid.

机译：妊娠期下尿路感染和无症状菌尿是常见的。2018年，我们得出结论，在妊娠的前三个月，头孢呋辛或阿莫西林+克拉维酸可能是比磷霉素氨丁三醇更谨慎的选择，并具有类似的疗效（1）。2019年，新的法国数据基于上加隆约5900名接触磷霉素氨丁三醇的孕妇，包括2600名在妊娠早期接触磷霉素氨丁三醇的孕妇，没有显示该药物导致畸形的风险增加（2）。在实践中，单剂量给药磷霉素氨丁三醇是孕妇妊娠早期下尿路感染的一种选择，头孢呋辛或阿莫西林+克拉维酸的组合也是如此。

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《Prescrire international》 |2020年第216期|共1页
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机译：单剂量磷霉素特罗美他莫在妊娠中期是否是无症状菌尿的良好替代品？
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Fosfomycin trometamol during the first trimester of pregnancy: new data

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