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Neural correlates of preserved facial affect perception in high functioning schizophrenia

机译:在高功率精神分裂症中保存面部影响感知的神经相关性

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Abstract Individuals with ‘high functioning’ schizophrenia (HF-SCZ) may have preserved facial affect perception (FAP) compared to individuals with ‘low functioning’ schizophrenia (LF-SCZ). The neural mechanisms supporting preserved FAP in HF-SCZ have yet to be evaluated. This study compared brain activation during FAP performance in HF-SCZ, LF-SCZ, and controls. Results demonstrated greater activation in the precuneus in CON compared to both SCZ groups, while HF-SCZ activated this region intermediate to controls and LF-SCZ. These preliminary findings suggest greater precuneus activation may be related to preserved FAP in HF-SCZ compared to LF-SCZ, though future research is needed to further evaluate differences between groups. Highlights ? High-functioning schizophrenia participants show intact facial affect perception. ? Controls had greater precuneus activation compared to schizophrenia groups. ? High-functioning schizophrenia had an intermediate level of precuneus activation. ? Precuneus activation may be related to intact performance in this population.
机译:摘要与“低功能”精神分裂症(LF-SCZ)患者相比,“高功能”精神分裂症(HF-SCZ)患者可能保留了面部情感感知(FAP)。支持HF-SCZ中保存FAP的神经机制尚待评估。本研究比较了HF-SCZ、LF-SCZ和对照组在FAP期间的大脑激活情况。结果显示,与两个SCZ组相比,CON组的楔前叶激活更大,而HF-SCZ激活了对照组和LF-SCZ的中间区域。这些初步研究结果表明,与LF-SCZ相比,HF-SCZ中更大的楔前叶激活可能与保存的FAP有关,尽管需要进一步研究来评估各组之间的差异。亮点?功能亢进的精神分裂症患者表现出完整的面部情感感知?与精神分裂症组相比,对照组有更大的楔前激活?高功能性精神分裂症有中度楔前激活?楔前叶激活可能与该人群的完整表现有关。

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