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首页> 外文期刊>Psychiatry Research. Neuroimaging >Cyclothymic temperament and glucose metabolism in the right superior parietal lobule
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Cyclothymic temperament and glucose metabolism in the right superior parietal lobule

机译：右高级顶叶的循环气质和葡萄糖代谢

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Abstract Cyclothymic temperament possesses a central dimension that includes rapid fluctuations in mood and emotional instability, and it is regarded as a prodromal state of bipolar disorder. The aim of the present study is to explore the neural correlates of cyclothymic temperament. We used the data of 55 healthy participants in our previous study and analyzed the association between cyclothymic temperament scores rated by the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire (TEMPS-A) and the uptake of [ 18 F]-FDG measured by positron emission tomography (PET). A whole brain analysis revealed a cluster of [ 18 F]-FDG uptake significantly and positively associated with cyclothymic temperament scores, located in the right superior parietal lobule (SPL). Even after adjustment for relevant factors, there remained a significant cluster of [ 18 F]-FDG uptake with cyclothymic temperament scores in the right SPL. In ROI analyses, there were similar significant peaks in the right SPL in association with cyclothymic temperament scores. These findings suggest that the right superior parietal lobule may be one of the neural correlates of cyclothymic temperament. Highlights ? A whole brain analysis revealed a cluster of [ 18 F]-FDG associated with cyclothymic temperament. ? The cluster is in the right superior parietal lobule (SPL). ? The right SPL may be one of the neural correlates of cyclothymic temperament.
机译：环胸腺气质具有一个中心维度，包括情绪的快速波动和情绪不稳定，被认为是双相情感障碍的前驱状态。本研究旨在探讨环胸腺气质的神经相关因素。我们在之前的研究中使用了55名健康参与者的数据，并分析了孟菲斯、比萨、巴黎和圣地亚哥自动问卷（TEMPS-A）的气质评估评分与正电子发射断层扫描（PET）测量的[18 F]-FDG摄取之间的关联。全脑分析显示[18 F]-FDG摄取与右顶叶（SPL）的环胸腺气质评分显著正相关。即使在对相关因素进行调整后，在右侧SPL中仍有一组[18 F]-FDG摄取与环胸腺气质评分显著相关。在ROI分析中，与环胸腺气质评分相关的右侧SPL也有类似的显著峰值。这些发现表明，右侧顶上小叶可能是环胸腺气质的神经相关因素之一。亮点？全脑分析显示[18F]-FDG簇与环胸腺气质有关？簇位于右侧顶上小叶（SPL）？右侧SPL可能是环胸腺气质的神经相关因素之一。

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