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首页> 外文期刊>Taiwan Veterinary Journal >A SEVERITY SCORING SYSTEM FOR OUTCOME PREDICTION IN CATS WITH PANCREATITIS
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A SEVERITY SCORING SYSTEM FOR OUTCOME PREDICTION IN CATS WITH PANCREATITIS

机译：胰腺炎猫的结果预测严重性评分系统

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摘要

In order to develop a clinically applicable severity scoring system in cats with pancreatitis, 41 cats diagnosed with pancreatitis and hospitalized between 2011 and 2013 with their complete medical history were selected for analysis. Clinical signs, physical examination findings, laboratory findings, diagnostic imaging results, complications and concurrent diseases were analyzed to evaluate potential prognostic factors and further establish the severity scoring system. The mortality of cats selected in this study due to pancreatitis was 48.8%. Abnormalities in hemoglobin, albumin, blood urea nitrogen, total bilirubin, phosphorous and blood pressure were significantly associated with disease severity and prognosis and were selected for constructing the system. The abnormal range for each variable was further partitioned into quartiles, which were recorded into categorical variables. The weighting factors were calculated from the odds ratios (OR) between each of the quartiles and the normal range category. The area under curve (AUC) of the six continuous variables system at presentation and after rehydration of the cats was 0.873 and 0.976, respectively. The scores of 41 cats after rehydration ranged from 7 to 36 points. The mean score was 19.7±8, the median 17 points and the mode 32 points. The optimal cut-off point for outcome prediction was 17.5 with a sensitivity of 95.2% and specificity of 95.5%. The mortality was 95% with a score≥18, whereas 4.8 % had a score≤17. The severity scoring system provides a reliable and clinically applicable method to predict disease severity in cats with pancreatitis.
机译：为了在患有胰腺炎的猫身上开发一个临床适用的严重性评分系统，选择了41只在2011年至2013年期间确诊患有胰腺炎并住院且有完整病史的猫进行分析。分析临床体征、体检结果、实验室检查结果、诊断影像学结果、并发症和并发疾病，以评估潜在的预后因素，并进一步建立严重程度评分系统。本研究选择的猫因胰腺炎的死亡率为48.8%。血红蛋白、白蛋白、血尿素氮、总胆红素、磷和血压的异常与疾病严重程度和预后显著相关，并被选为构建该系统的指标。每个变量的异常范围进一步划分为四分位数，并记录到分类变量中。加权因子根据每个四分位数与正常范围类别之间的优势比（OR）计算。猫出现时和补液后六个连续变量系统的曲线下面积（AUC）分别为0.873和0.976。41只猫在补液后的得分从7分到36分不等。平均得分为19.7±8分，中位数为17分，模式为32分。结果预测的最佳临界点为17.5，敏感性为95.2%，特异性为95.5%。死亡率为95%，评分为a≥18%，而4.8%的人得分≤17.严重程度评分系统为预测患有胰腺炎的猫的疾病严重程度提供了可靠且临床适用的方法。

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