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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Risk Factors for Death Among 120,804 Hospitalized Patients with Confirmed COVID-19 in Sao Paulo, Brazil
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Risk Factors for Death Among 120,804 Hospitalized Patients with Confirmed COVID-19 in Sao Paulo, Brazil

机译：巴西圣保罗的40,804名住院患者死亡危险因素

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摘要

Sao Paulo is a state in Brazil with one of the highest numbers of confirmed and severe cases of coronavirus disease (COVID-19), with an incidence of 294 hospitalizations per 100,000 inhabitants. We report the clinical characteristics and outcomes of 120,804 hospitalized patients with confirmed COVID-19 from February 26 to October 10, 2020, in Sao Paulo. Characteristics of patients who died and survived were compared using a survival analysis. The median age was 60 years (interquartile range [IQR], 47-72), 67,821 (56.1%) were men, and 61,659 (51.0%) were white. Most hospitalized patients (79,812; 66.1%) reported one or more comorbidities, 41,708 (34.5%) hospitalized patients were admitted to intensive care units, and 33,079 (27.4%) died. Men (hazard ratio [HR], 1.22; 95% confidence interval [CI], 1.18-1.25), elderly individuals (HR, 3.85; 95% CI, 3.68-4.02), and patients with chronic cardiovascular disease including hypertension (HR, 1.05; 95% CI, 1.02-1.08), chronic lung disease (HR, 1.38; 95% CI, 1.31-1.45), diabetes mellitus (HR, 1.14; 95% CI, 1.11-1.18), and chronic neurological disease (HR, 1.48; 95% CI, 1.41-1.55) were at higher risk for death from COVID-19.
机译：圣保罗州是巴西确诊和严重冠状病毒病（新冠肺炎-19）病例最多的州之一，每10万居民中有294例住院。我们报告了120804 2019冠状病毒疾病的住院患者的临床特征和结果，2月26日至2020年10月10日在圣保罗。使用生存分析比较死亡和存活患者的特征。中位年龄为60岁（四分位间距[IQR]，47-72），男性67821人（56.1%），白人61659人（51.0%）。大多数住院患者（79812例；66.1%）报告有一种或多种共病，41708例（34.5%）住院患者入住重症监护病房，33079例（27.4%）死亡。男性（危险比[HR]为1.22；95%可信区间[CI]为1.18-1.25）、老年人（HR为3.85；95%可信区间为3.68-4.02）和慢性心血管疾病患者，包括高血压（HR为1.05；95%可信区间为1.02-1.08）、慢性肺病（HR为1.38；95%可信区间为1.31-1.45）、糖尿病（HR为1.14；95%可信区间为1.11-1.18），2019冠状病毒疾病的危险性较高，慢性神经系统疾病（HR，1.48；95% CI，1.41-1.55）。

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