...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005-2010
【24h】

Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005-2010

机译：2005 - 2010年塞内加尔的控制干预措施增加，疟疾负担和全因儿童死亡率的下降

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Malaria is endemic in Senegal. The national malaria control strategy focuses on achieving universal coverage for major interventions, with a goal of reaching preelimination status by 2018. Senegal began distribution of insecticide-treated nets (ITNs) and introduced artemisinin-based combination therapy in 2006, then introduced rapid diagnostic tests in 2007. We evaluated the impact of these efforts using a plausibility design based on malaria's contribution to all-cause under-five mortality (ACCM) and considering other contextual factors which may influence ACCM. Between 2005 and 2010, household ownership of ITNs increased from 20% to 63%, and the proportion of people sleeping under an ITN the night prior to the survey increased from 6% to 29%. Malaria parasite prevalence declined from 6% to 3% from 2008 to 2010 among children under five. Some nonmalaria indicators of child health improved, for example, increase of complete vaccination coverage from 58% to 64%; however, nutritional indicators deteriorated, with an increase in stunting from 16% to 26%. Although economic indicators improved, environmental conditions favored an increase in malaria transmission. ACCM decreased 40% between 2005 and 2010, from 121 (95% confidence interval [CI] 113-129) to 72 (95% CI 66-77) per 1,000, and declines were greater among age groups, epidemiologic zones, and wealth quintiles most at risk for malaria. After considering coverage of malaria interventions, trends in malaria morbidity, effects of contextual factors, and trends in ACCM, it is plausible that malaria control interventions contributed to a reduction in malaria mortality and to the impressive gains in child survival in Senegal.
机译：疟疾是塞内加尔的地方病。国家疟疾控制战略的重点是实现主要干预措施的全民覆盖，目标是到2018年达到消除疟疾前状态。塞内加尔开始分发驱虫蚊帐（ITN），并于2006年引入青蒿素类联合疗法，然后于2007年引入快速诊断试验。我们基于疟疾对五岁以下儿童全因死亡率（ACCM）的贡献，并考虑可能影响ACCM的其他环境因素，采用合理性设计评估了这些努力的影响。2005年至2010年间，ITN的家庭拥有率从20%上升到63%，调查前一晚睡在ITN下的人比例从6%上升到29%。从2008年到2010年，五岁以下儿童的疟疾寄生虫患病率从6%下降到3%。儿童健康的一些非疟疾指标有所改善，例如，疫苗接种覆盖率从58%提高到64%；然而，营养指标恶化，发育迟缓率从16%增加到26%。尽管经济指标有所改善，但环境条件有利于疟疾传播的增加。2005年至2010年期间，ACCM下降了40%，从121（95%置信区间[CI]113-129）降至72（95%置信区间66-77），且在疟疾风险最高的年龄组、流行病学区域和财富五分位数中下降幅度更大。在考虑了疟疾干预措施的覆盖范围、疟疾发病率的趋势、环境因素的影响以及ACCM的趋势之后，疟疾控制干预措施似乎有助于降低疟疾死亡率，并使塞内加尔的儿童存活率获得显著提高。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号