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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Spatiotemporal Heterogeneity of Zika Virus Transmission in Indonesia: Serosurveillance Data from a Pediatric Population
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Spatiotemporal Heterogeneity of Zika Virus Transmission in Indonesia: Serosurveillance Data from a Pediatric Population

机译：印度尼西亚Zika病毒传播的时空异质性：儿科人口的血清素数据

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摘要

The presence of Zika virus (ZIKV) in Indonesia has been recognized since the 1970s, but its transmission dynamics there have been poorly understood. To understand more fully the geographic distribution and burden of ZIKV infection, we performed retrospective serological tests on specimens collected from asymptomatic children age 5 to 9 years old living at 30 sites in 14 provinces. Of 870 serum samples tested, 9.2% were found to be positive for anti-ZIKV antibodies, as confirmed by plaque reduction neutralization assays. This was the same overall prevalence reported previously for 1-to 4-year-old children collected at the same sites at the same time. Together with geographic differences in seroprevalence between the age groups, these data suggest that, although ZIKV might be endemic in Indonesia, its occurrence has been focal and episodic.
机译：自20世纪70年代以来，人们已经认识到寨卡病毒（ZIKV）在印度尼西亚的存在，但对其在那里的传播动态知之甚少。为了更全面地了解ZIKV感染的地理分布和负担，我们对来自14个省份30个地点的5至9岁无症状儿童的样本进行了回顾性血清学检测。在870份检测的血清样本中，9.2%的抗ZIKV抗体呈阳性，这一点通过斑块减少中和试验得到证实。这与之前在同一时间在同一地点收集的1至4岁儿童的总体患病率相同。加上各年龄组之间血清流行率的地理差异，这些数据表明，尽管ZIKV可能在印度尼西亚流行，但它的发生是局部和偶发的。

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