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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case Report: Ischemic Colitis in Severe COVID-19 Pneumonia: An Unforeseen Gastrointestinal Complication
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Case Report: Ischemic Colitis in Severe COVID-19 Pneumonia: An Unforeseen Gastrointestinal Complication

机译：病例报告：严重Covid-19肺炎中的缺血性结肠炎：不可预见的胃肠道并发症

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摘要

Clinical manifestations and complications of SARS-CoV-2 are still emerging and variant. Gastrointestinal (GI) manifestations and complications are hugely under-recognized. The presence of angiotensin converting enzyme-2 receptors in the intestinal enterocytes, the receptors primarily involved in the pathogenesis of COVID-19 pneumonia, maybe the key factor contributing to the pathogenesis of GI manifestations. Ischemic colitis, although the most common ischemic pathology of the GI tract, is relatively rare, occurring as a result of colonic hypoperfusion. The innumerable causes of colonic ischemia are categorized into occlusive and nonocclusive pathologies. Here, we have discussed a case of severe COVID-19 pneumonia, developing ischemic colitis, as a rare GI complication. The cause of ischemia in COVID19 pneumonia is multifactorial, including hypercoagulable state, coagulopathy leading to thromboembolic complications, and use of vasopressors in severely ill patients with hemodynamic compromise.
机译：SARS-CoV-2的临床表现和并发症仍在出现和变异。胃肠道（GI）表现和并发症的认识严重不足。2019冠状病毒疾病的发病机制中，血管紧张素转换酶-2受体在肠肠细胞中的存在，主要参与COVID-19肺炎的发病机制。缺血性结肠炎虽然是胃肠道最常见的缺血性病变，但由于结肠灌注不足而发生的情况相对少见。结肠缺血的原因可分为闭塞性和非闭塞性病变。在这里，我们2019冠状病毒疾病，发展为缺血性肠炎，作为一种罕见的胃肠道并发症。COVID19肺炎缺血的原因是多因素的，包括高凝状态、导致血栓栓塞并发症的凝血障碍，以及血液动力学受损的重症患者使用血管升压药。

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