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首页> 外文期刊>The British journal of psychiatry : >Incidence of ischaemic heart disease and stroke among people with psychiatric disorders: retrospective cohort study
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Incidence of ischaemic heart disease and stroke among people with psychiatric disorders: retrospective cohort study

机译：缺血性心脏病发病率和精神病患者人群中风：回顾性队列研究

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Background Psychiatric disorders are associated with increased risk of ischaemic heart disease (IHD) and stroke, but it is not known whether the associations or the role of sociodemographic factors have changed over time. Aims To investigate the association between psychiatric disorders and IHD and stroke, by time period and sociodemographic factors. Method We used Scottish population-based records from 1991 to 2015 to create retrospective cohorts with a hospital record for psychiatric disorders of interest (schizophrenia, bipolar disorder or depression) or no record of hospital admission for mental illness. We estimated incidence and relative risks of IHD and stroke in people with versus without psychiatric disorders by calendar year, age, gender and area-based deprivation level. Results In all cohorts, incidence of IHD (645 393 events) and stroke (276 073 events) decreased over time, but relative risks decreased for depression only. In 2015, at the mean age at event onset, relative risks were 2- to 2.5-fold higher in people with versus without a psychiatric disorder. Age at incidence of outcome differed by cohort, gender and socioeconomic status. Relative but not absolute risks were generally higher in women than men. Increasing deprivation conveys a greater absolute risk of IHD for people with bipolar disorder or depression. Conclusions Despite declines in absolute rates of IHD and stroke, relative risks remain high in those with versus without psychiatric disorders. Cardiovascular disease monitoring and prevention approaches may need to be tailored by psychiatric disorder and cardiovascular outcome, and be targeted, for example, by age and deprivation level.
机译：背景精神障碍与缺血性心脏病（IHD）和中风风险增加有关，但不知道社会人口因素的关联或作用是否随着时间的推移而改变。目的通过时间段和社会人口统计学因素调查精神障碍与IHD和中风之间的关系。方法：我们使用1991年至2015年的苏格兰人群记录，创建有感兴趣的精神疾病（精神分裂症、双相情感障碍或抑郁症）住院记录或没有精神疾病住院记录的回顾性队列。我们根据日历年、年龄、性别和基于地区的剥夺水平，估计了精神障碍患者与非精神障碍患者IHD和中风的发病率和相对风险。结果在所有队列中，IHD（645393个事件）和中风（276073个事件）的发生率随着时间的推移而降低，但仅抑郁症的相对风险降低。2015年，在事件发生的平均年龄，有精神障碍的人的相对风险比没有精神障碍的人高2到2.5倍。结果发生的年龄因队列、性别和社会经济地位而异。女性的相对风险（而非绝对风险）通常高于男性。对双相情感障碍或抑郁症患者来说，日益严重的剥夺意味着患IHD的绝对风险更大。结论尽管IHD和中风的绝对发病率有所下降，但精神障碍患者与非精神障碍患者的相对风险仍然较高。心血管疾病的监测和预防方法可能需要根据精神障碍和心血管结局进行调整，并以年龄和剥夺程度为目标。

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