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Neoteric advancements in TB diagnostics and its future frame

机译:结核病诊断的近期进步及其未来框架

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Tuberculosis (TB) is one of the major infectious disease that causes threat to human health and leads to death in most of the cases. Mycobacterium tuberculosis is the causative agent that can affect both pulmonary and extra pulmonary regions of the body. This infection can be presented either as an active or latent form in the patients. Although this disease has been declared curable and preventable by WHO, it still holds its position as a global emergency. Over the past decade many hurdles such as low immunity, co-infections like HIV, autoimmune disorders, poverty, malnutrition and emerging trends in drug resistance patterns are hindering the eradication of this infection. However, many programmes have been launched by WHO with involvement of governments at various level to put a full stop over the disease. Under the Revised National Tuberculosis Control Programme (RNTCP) which was recently renamed as National Tuberculosis Elimination Programme (NTEP), the major focus is on eliminating tuberculosis by the year 2025. The main aim of the programme is to identify feasible quality testing, evaluate through NIKSHYA poshak yozana, restrict through BCG vaccination and assemble with public awareness to eradicate MTB. Numerous novel diagnostic techniques and molecular tools have been developed to elucidate and differentiate report of various suspected and active tuberculosis patients. However, improvements are still required to cut short the duration of the overall process ranging from screening of patients to their successful treatment.
机译:肺结核(TB)是威胁人类健康并导致死亡的主要传染病之一。结核分枝杆菌是一种病原体,可影响身体的肺和肺外区域。这种感染在患者中可以表现为活动或潜伏形式。尽管世卫组织已宣布这种疾病可以治愈和预防,但它仍然是一种全球紧急情况。在过去十年中,免疫力低下、艾滋病毒等共同感染、自身免疫性疾病、贫困、营养不良和耐药性模式的新趋势等许多障碍阻碍了这种感染的根除。然而,世卫组织在各级政府的参与下启动了许多方案,以彻底结束该疾病。修订后的国家结核病控制计划(RNTCP)最近更名为国家消灭结核病计划(NTEP),其主要重点是到2025年消灭结核病。该计划的主要目的是确定可行的质量检测,通过NIKSHYA poshak yozana进行评估,通过卡介苗接种进行限制,并与公众一起提高根除MTB的意识。许多新的诊断技术和分子工具已经被开发出来,以阐明和区分各种疑似和活动性肺结核患者的报告。然而,仍然需要改进,以缩短从患者筛查到成功治疗的整个过程的持续时间。

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