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首页> 外文期刊>The Canadian journal of hospital pharmacy. >Correlation between Medication Administration-Related Errors in Patients with Parkinson Disease and Timing of Pharmacy-Led Best Possible Medication Histories
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Correlation between Medication Administration-Related Errors in Patients with Parkinson Disease and Timing of Pharmacy-Led Best Possible Medication Histories

机译:帕金森病患者药物施用相关误差与药学LED最佳药物历史的时序相关性

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Background: Poor prescribing and incomplete medication administration have been linked to increased lengths of hospitalization for patients with Parkinson disease. The Institute for Safe Medication Practices (ISMP) has recommended that patients with Parkinson disease receive a pharmacy consultation within 2 h of admission to hospital. Objectives: To examine whether the time for a pharmacy team member to obtain a best possible medication history (BPMH) was associated with administration-related medication errors. The primary outcome was the proportion of doses with a medication error during a patient’s admission in relation to the time to completion of the initial BPMH by a registered pharmacist (RPh) or registered pharmacy technician (RPhT). The secondary objective was to compare the proportion of doses with a medication error in relation to whether the BPMH was completed by an RPh or an RPhT. Methods: This retrospective chart review involved patients with Parkinson disease who were admitted to the medicine services at London Health Sciences Centre from September 30, 2014, to September 30, 2018. Patients were included if they had Parkinson disease and a medication regimen that included levodopa-carbidopa. For all patients, an RPhT or RPh conducted the initial BPMH or updated the BPMH. Pearson correlation analysis was used to determine whether a correlation existed between administration-related errors and completion of the BPMH by a pharmacy staff member. Results: A total of 84 patients with 104 admissions were included. There was no significant correlation between the time to completion of the initial BPMH by a pharmacy team member and the proportion of doses with medication errors (p = 0.32). Although RPhTs completed the BPMHs more quickly than RPhs (p < 0.001), there was no significant difference between pharmacy team members in terms of the proportion of doses with medication errors (p = 0.86). Conclusions: Completing a BPMH within 2 h of a patient’s admission, as per the ISMP recommendation, is unlikely to affect administration-related medication errors, given that no correlation was identified. Expediting BPMH without addressing other factors is insufficient, and initiatives are required to improve the medication administration process.
机译:背景:不良的处方和不完整的药物管理与帕金森病患者住院时间延长有关。安全用药实践研究所(ISMP)建议帕金森病患者在入院后2小时内接受药学咨询。目的:研究药房团队成员获得最佳用药史(BPMH)的时间是否与给药相关的用药错误有关。主要结果是患者入院期间出现药物错误的剂量与注册药剂师(RPh)或注册药剂师(RPhT)完成初始BPMH的时间的比例。第二个目标是比较药物错误的剂量比例与BPMH是否由RPh或RPhT完成的关系。方法:这项回顾性图表回顾涉及2014年9月30日至2018年9月30日在伦敦健康科学中心接受医疗服务的帕金森病患者。如果患者患有帕金森病,并采用包括左旋多巴卡比多巴在内的药物治疗方案,则纳入研究。对于所有患者,RPhT或RPh进行初始BPMH或更新BPMH。Pearson相关分析用于确定与管理相关的错误与药房工作人员完成BPMH之间是否存在相关性。结果:共纳入84例患者,104例入院。药房团队成员完成初始BPMH的时间与出现用药错误的剂量比例之间没有显著相关性(p=0.32)。尽管RPHT完成BPMHs的速度比RPhs快(p<0.001),但在有药物错误的剂量比例方面,药房团队成员之间没有显著差异(p=0.86)。结论:根据ISMP建议,在患者入院后2小时内完成BPMH不太可能影响与给药相关的药物错误,因为没有发现相关性。在不解决其他因素的情况下加快BPMH是不够的,需要采取措施来改进给药过程。

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