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Incidentaloma Discoveries in the Course of Neuroimaging Research

机译:在神经影像动物研究过程中发现偶然瘤

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摘要

Among healthy volunteers in psychiatric brain functional magnetic resonance imaging (fMRI) research studies, the prevalence of incidentalomas can be as high as 34%, of which 10% show clinical significance. An incidentaloma is a lesion found by coincidence without clinical symptoms or suspicion. Like lesions and other types of accidental findings, it is found in healthy individuals recruited to take part in psychiatric studies. The prevalence of these accidental findings among specific psychiatric populations remains unknown. However, a precise understanding of cerebral neuroanatomy, neuroradiological expertise, and an appropriate choice of fMRI exploration sequences will increase the sensitivity of identifying these accidental findings and enable researchers to address their clinical relevance and nature. We present recommendations on how to appropriately inform patients or participants of the accidental findings. Additionally, we propose specific suggestions pertaining to the clinical research setting aimed for investigators and psychiatrists. Unlike current articles pertaining to incidentaloma, the current report provides a distinct focus on psychiatric issues and specific recommendations for studies involving psychiatric patients.
机译:在精神科脑功能磁共振成像(fMRI)研究的健康志愿者中,偶发瘤的患病率高达34%,其中10%具有临床意义。偶发瘤是指在没有临床症状或怀疑的情况下偶然发现的病变。像病变和其他类型的意外发现一样,它也在被招募参加精神病学研究的健康个体中发现。这些意外发现在特定精神病人群中的流行率仍然未知。然而,对大脑神经解剖学、神经放射学专业知识的精确理解,以及功能磁共振成像探测序列的适当选择,将提高识别这些意外发现的敏感性,并使研究人员能够解决其临床相关性和性质。我们就如何恰当地将意外发现告知患者或参与者提出建议。此外,我们还针对调查人员和精神科医生提出了与临床研究环境相关的具体建议。与目前有关偶发瘤的文章不同,本报告对精神病问题给予了明确关注,并对涉及精神病患者的研究提出了具体建议。

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