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Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic

机译:Covid-19大流行的神经系统和神经精神症

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Background: Albeit primarily a disease of respiratory tract, the 2019 coronavirus infectious disease (COVID-19) has been found to have causal association with a plethora of neurological, neuropsychiatric and psychological effects. This review aims to analyze them with a discussion of evolving therapeutic recommendations. Methods: PubMed and Google Scholar were searched from 1 January 2020 to 30 May 2020 with the following key terms: "COVID-19", "SARS-CoV-2", "pandemic", "neuro-COVID", "stroke-COVID", "epilepsy-COVID", "COVID-encephalopathy", "SARS-CoV-2-encephalitis", "SARS-CoV-2-rhabdomyolysis", "COVID-demyelinating disease", "neurological manifestations", "psychosocial manifestations", "treatment recommendations", "COVID-19 and therapeutic changes", "psychiatry", "marginalised", "telemedicine", "mental health", "quarantine", "infodemic" and "social media". A few newspaper reports related to COVID-19 and psychosocial impacts have also been added as per context. Results: Neurological and neuropsychiatric manifestations of COVID-19 are abundant. Clinical features of both central and peripheral nervous system involvement are evident. These have been categorically analyzed briefly with literature support. Most of the psychological effects are secondary to pandemic-associated regulatory, socioeconomic and psychosocial changes. Conclusion: Neurological and neuropsychiatric manifestations of this disease are only beginning to unravel. This demands a wide index of suspicion for prompt diagnosis of SARS-CoV-2 to prevent further complications and mortality.
机译:背景:2019年新冠病毒感染性疾病(COVID-19)虽然主要是呼吸道疾病,但已被发现与过多的神经、神经精神和心理影响有因果关系。本综述旨在通过讨论不断发展的治疗建议来分析它们。方法:从2020年1月1日至2020年5月30日,在PubMed和Google Scholar上搜索以下关键词:“COVID-19”、“SARS-CoV-2”、“大流行”、“神经-COVID”、“中风-COVID”、“癫痫-COVID”、“COVID脑病”、“SARS-CoV-2-脑炎”、“SARS-CoV-2-横纹肌溶解症”、“COVID脱髓鞘病”、“神经表现”、“心理社会表现”,“治疗建议”、“新冠肺炎和治疗变化”、“精神病学”、“边缘化”、“远程医疗”、“心理健康”、“隔离”、“信息医学”和“社交媒体”。一些报纸报道与2019冠状病毒疾病和心理社会影响也被添加到每个上下文。结果:2019冠状病毒疾病的神经和精神症状表现丰富。中枢和外周神经系统受累的临床特征都很明显。在文献支持下,对这些问题进行了简要的分类分析。大多数心理影响都是大流行相关的监管、社会经济和心理社会变化的次要影响。结论:这种疾病的神经和神经精神表现才刚刚开始解开。这需要一个广泛的怀疑指数,以便及时诊断SARS-CoV-2,以防止进一步的并发症和死亡率。

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