A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation.

Fujita Y; Murakami R; Muramatsu Y; Miyakoshi S; Takatsu T

首页> 外文期刊>The Journal of Antibiotics: An International Journal >A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation.

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A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation.

机译：A-94964，由Streptomyces SP产生的细菌易位酶I的新型抑制剂。 SANK 60404.II。物理化学性质和结构阐明。

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In our screening for translocase I inhibitors, we found the novel nucleoside antibiotic, A-94964 in the culture broth of Streptomyces sp. SANK 60404. The structure of A-94964 was elucidated primarily by various NMR studies, including a 1H-31P HMBC experiment. A-94964 has a unique structure which possesses a nucleoside moiety and an N-acylglucosamine moiety connected via a phosphate.

机译：在我们对易位酶I抑制剂的筛选中，我们在链霉菌S60404的培养液中发现了新型核苷抗生素A-94964。A-94964的结构主要通过各种NMR研究得到阐明，包括1H-31P HMBC实验。A-94964具有独特的结构，它拥有一个核苷部分和一个通过磷酸盐连接的N-酰基葡萄糖胺部分。

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《The Journal of Antibiotics: An International Journal》 |2008年第9期|共5页
作者
Fujita Y; Murakami R; Muramatsu Y; Miyakoshi S; Takatsu T;
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Exploratory Research Laboratories I Daiichi-Sankyo Co. Ltd. 1-2-58 Hiromachi Shinagawa-ku;

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正文语种 eng
中图分类药学;
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1. A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation. [J] . Fujita Y, Murakami R, Muramatsu Y, The Journal of Antibiotics: An International Journal . 2008,第9期

机译：A-94964，一种由细菌链霉菌属产生的新型细菌转座酶I抑制剂。 SANK 60404。理化性质和结构阐明。
2. A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation. [J] . Fujita Y, Murakami R, Muramatsu Y, The Journal of Antibiotics: An International Journal . 2008,第9期

机译：A-94964，由Streptomyces SP产生的细菌易位酶I的新型抑制剂。 SANK 60404.II。物理化学性质和结构阐明。
3. A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation. [J] . Fujita Y, Murakami R, Muramatsu Y, The Journal of Antibiotics: An International Journal . 2008,第9期

机译：A-94964，由Streptomyces SP产生的细菌易位酶I的新型抑制剂。 SANK 60404.II。物理化学性质和结构阐明。
4. Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties [O] . Marija Mojicevic, Paul M. DAgostino, Aleksandar Pavic, 2020

机译：链霉菌洋甘菊根际土壤中的BV410分离物可有效产生具有抗真菌和抗血管生成特性的星形孢菌素
5. A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404 [O] . Ryo Murakami, Yoko Fujita, Masaaki Kizuka, 2008

机译：A-94964，一种新型细菌型千磷酶I抑制剂，由Streptomyces Sp产生。沉没60404.

A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation.

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