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首页> 外文期刊>The Journal of dermatology >Heterogeneity in the linear shiny white structures in melanomas seen with polarized light according to histopathological association: Cross-sectional observational study in 118 cutaneous melanomas
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Heterogeneity in the linear shiny white structures in melanomas seen with polarized light according to histopathological association: Cross-sectional observational study in 118 cutaneous melanomas

机译：根据组织病理学协会的偏振光（偏振光）的线性发光白色结构中的异质性：118皮肤黑色瘤中的横截面观察研究

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摘要

Polarized dermoscopy enables visualization of linear shiny white structures in melanomas, thought to be due to the existence of fibrosis in the dermis. Our objective was to establish the existence of two types of linear shiny white structures and assess their association with different histological structures. We performed a cross-sectional study including all non-acral, non-facial melanomas from our hospital with linear shiny white structures. The outcome variable was the type of linear shiny white structures: shiny white streaks and white strands. We evaluated their association with explanatory variables that may affect the reflectance of melanomas and Breslow index. We used chi(2)statistics and also calculated the sensitivity and specificity of each linear shiny white structure to predict those variables. We detected linear shiny white structures in 118 melanomas. Regarding shiny white streaks, we only found a statistically significant positive relationship with fibrosis in the papillary dermis. Regarding white strands, we found statistically significant and positive relationships with hyperkeratosis, Breslow index of 0.8 mm or more and acanthosis. Sensitivity and specificity study revealed that the presence of shiny white streaks was the most sensitive (81.7%) and specific (72.3%) for fibrosis in the papillary dermis, and presence of white strands was the most sensitive (91.1%) and specific (85.7%) for hyperkeratosis.
机译：偏振皮肤镜检查可以显示黑色素瘤中的线性闪亮白色结构，这被认为是由于真皮中存在纤维化。我们的目标是确定两种线性亮白色结构的存在，并评估它们与不同组织结构的关系。我们进行了一项横断面研究，包括我们医院的所有非肢端、非面部黑色素瘤，其结构呈线性亮白色。结果变量是线性亮白色结构的类型：亮白色条纹和白色链。我们评估了它们与可能影响黑色素瘤反射率和Breslow指数的解释变量之间的关联。我们使用chi（2）统计数据，还计算了每个线性闪亮白色结构的敏感性和特异性，以预测这些变量。我们在118例黑色素瘤中检测到线性亮白色结构。关于闪亮的白色条纹，我们只发现与真皮乳头状组织的纤维化有统计学意义的正相关。关于白链，我们发现与角化过度、Breslow指数大于等于0.8 mm和棘皮病有统计学意义的正相关关系。敏感性和特异性研究表明，对于乳头状真皮纤维化，亮白色条纹的存在最敏感（81.7%）和特异性（72.3%），而对于角化过度，白色条纹的存在最敏感（91.1%）和特异性（85.7%）。

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