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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Effect of Computerized Physician Order Entry and Clinical Decision Support System on Adverse Drug Events Prevention in the Emergency Department: A Systematic Review
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Effect of Computerized Physician Order Entry and Clinical Decision Support System on Adverse Drug Events Prevention in the Emergency Department: A Systematic Review

机译：计算机化医师订单进入和临床决策支持系统对急诊部门不良药物事件的影响：系统审查

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Objective: An adverse drug event (ADE) is an injury resulting from a medical intervention related to a drug. The emergency department (ED) is a ward vulnerable to more ADEs because of overcrowding. Information technologies such as computerized physician order entry (CPOE) and clinical decision support system (CDSS) may decrease the occurrence of ADEs. This study aims to review research that reported the evaluation of the effectiveness of CPOE and CDSS on lowering the occurrence of ADEs in the ED. Data Sources: PubMed, EMBASE, and Web of Science databases were used to find studies published from 2003 to 2018. The search was conducted in November 2018. Study Selection and Data Extraction: The search resulted in 1700 retrieved articles. After applying inclusion and exclusion criteria, 11 articles were included. Data on the date, country, type of system, medication process stages, study design, participants, sample size, and outcomes were extracted. Data Synthesis: Results showed that CPOE and CDSS may prevent ADEs in the ED through significantly decreasing the rate of errors, ADEs, excessive dose, and inappropriate prescribing (in 54.5% of articles); furthermore, CPOE and CDSS may significantly increase the rate of appropriate prescribing and dosing in compliance with established guidelines (45.5% of articles). Conclusion: This study revealed that the use of CPOE and CDSS can lower the occurrence of ADEs in the ED; however, further randomized controlled trials are needed to address the effect of a CDSS, with basic or advanced features, on the occurrence of ADEs in the ED.
机译：目的：药物不良事件（ADE）是与药物相关的医疗干预导致的伤害。急诊室（ED）是一个因过度拥挤而容易发生更多ADE的病房。计算机医嘱录入（CPOE）和临床决策支持系统（CDSS）等信息技术可以减少ADE的发生。本研究旨在回顾报告CPOE和CDSS在降低ED中ADE发生率方面的有效性评估的研究。数据来源：PubMed、EMBASE和科学网数据库用于查找2003年至2018年发表的研究。搜索于2018年11月进行。研究选择和数据提取：搜索结果为1700篇检索到的文章。应用纳入和排除标准后，纳入11篇文章。提取有关日期、国家、系统类型、用药过程阶段、研究设计、参与者、样本量和结果的数据。数据综合：结果显示，CPOE和CDSS可以通过显著降低错误率、ADE、过量剂量和不恰当处方（54.5%的文章）来预防ED中的ADE；此外，CPOE和CDSS可能会显著增加符合既定指南的适当处方和剂量（45.5%的文章）。结论：本研究表明，使用CPOE和CDSS可以降低ED中ADE的发生率；然而，需要进一步的随机对照试验来解决具有基本或高级特征的CDS对ED中ADE发生的影响。

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