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首页> 外文期刊>The New Zealand dental journal >Brown tumour of the mandible in primary hyperparathyroidism; a case report
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Brown tumour of the mandible in primary hyperparathyroidism; a case report

机译:原发性甲状旁腺功能亢进中下颌骨的棕色肿瘤; 案例报告

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摘要

We present an uncommon diagnosis in a 34-year-old female with a non-healing extraction socket. Incisional biopsy revealed multi-nucleated giant cells suggestive of central giant cell granuloma (CGCG). The computed tomography (CT) report made incidental note of a parathyroid mass. The parathyroid hormone (PTH) level was checked and found to be abnormally high. A diagnosis of brown tumour of the mandible was made. The patient was referred to a head and neck surgeon and the parathyroid mass was removed. The mandibular lesion was managed conservatively and continues to regress post-normalisation of PTH levels. The inclusion of the parathyroid region on the CT scan in this case was fortuitous. There are a range of pathologies containing multinucleated giant cells that can arise from the maxillofacial region; PTH level should, nevertheless, be checked in all such jaw lesions. This allows the clinician to exclude brown tumour from the diagnostic sieve.
机译:我们报告一例34岁女性拔牙窝不愈合的罕见诊断。切口活检显示多核巨细胞提示中央巨细胞肉芽肿(CGCG)。计算机断层扫描(CT)报告偶然发现甲状旁腺肿块。检查甲状旁腺激素(PTH)水平,发现异常高。诊断为下颌骨棕色肿瘤。患者被转诊至头颈部外科医生,甲状旁腺肿块被切除。下颌病变采用保守治疗,PTH水平正常化后继续消退。本例CT扫描中包含甲状旁腺区域是偶然的。有一系列包含多核巨细胞的病理学表现,这些巨细胞可以起源于颌面部;然而,在所有此类颌骨病变中都应检查PTH水平。这使得临床医生可以从诊断筛中排除棕色肿瘤。

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