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Concurrent Stroke and Myocardial Infarction After Mild COVID-19 Infection

机译:轻度Covid-19感染后的同时卒中和心肌梗死

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Introduction: The concurrency of both, acute stroke and acute myocardial infarction in normal conditions, outside the pandemic is rare. Coagulopathy has been associated with the inflammatory phase of coronavirus disease (COVID-19) and might be involved in this concurrency. Cases Report: We describe 2 patients with previous mild or no symptoms of COVID-19, admitted for acute stroke with recent/simultaneous myocardial infarction in whom admission polymerase chain reaction was negative but serologic testing diagnosed COVID-19. In these patients, concurrent stroke and myocardial infarction could have been promoted by COVID-19 infection. Management and evolution are detailed, and their contacts to confirm the COVID-19 infection. Pathogenic analysis of possible hypercoagulation state is described suggesting the hypothesis of endothelial dysfunction as the strongest mechanism involved in thrombus formation after the acute phase of COVID-19 infection. Conclusions: Our experience with these cases suggests that patients with mild symptoms can also present thromboembolic complications once the acute phase of COVID-19 infection has passed.
机译:导言:在正常情况下,在大流行之外,急性中风和急性心肌梗死同时发生是罕见的。凝血病与冠状病毒病(COVID-19)的炎症期有关,可能与此同时发生有关。2019冠状病毒疾病2019冠状病毒疾病患者的临床资料。我们报道了2例先前有轻度或无症状的COVID-19症状,并接受了近期或同时发生的心肌梗死患者,其中接受聚合酶链反应阴性,但血清学检测诊断为COVID-19。在这些患者2019冠状病毒疾病中,同时可以促进卒中和心肌梗死。2019冠状病毒疾病的详细描述,并与它们的联系进行确认,以证实COVID-19感染。描述了可能的高凝状态的致病性分析,提示内皮功能障碍是最强的机制参与血栓形成后急性期COVID-19感染。结论:2019冠状病毒疾病急性期患者的症状轻微,一旦COVID-19感染的急性期过去,也可出现血栓栓塞并发症。

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