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首页> 外文期刊>The American Journal of Cardiology >Feasibility of Transcatheter Closure of Secundum Atrial Septal Defect in Low Weight Infants Under 2-Year-Old from a 3-year Retrospective Cohort Study
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Feasibility of Transcatheter Closure of Secundum Atrial Septal Defect in Low Weight Infants Under 2-Year-Old from a 3-year Retrospective Cohort Study

机译：从3年的回顾性队列研究中，2岁以下的低重量婴儿的经转截面闭合闭塞梗死的可行性

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摘要

We aimed to evaluate the feasibility of interventional treatment of atrial septal defect (ASD) in low weight infants under 2-year-old. Seven hundred and ninety-three secundum ASD patients were divided into 2 groups: 665 were above 2-year-old and 128 were under 2-year-old. The basic conditions before the operation, postoperative complications within 24 hours, and adverse outcomes during a three-year follow-up were compared between the 2 groups using multivariate analysis. There were significant differences in age, weight, and the diameter of the ASD between the 2 groups (p 0.001). The immediate success rate of the procedure was 96.7%. There were no significant differences in the success rate of the procedure, the incidence of residual shunt, arrhythmia, procedure-related arrhythmia, and occluder shedding between 2 groups (p 0.05). Similarly, we found no association between age <= 2-year-old and any adverse outcomes postprocedure within 24 hours, including procedure failure (OR = 0.35; 95%CI: 0.04 to 2.93), residual shunt (OR = 1.07; 95%CI: 0.54 to 2.14), arrhythmia (OR = 0.68; 95%CI: 0.32 to 1.43), or procedure-related arrhythmia (OR = 0.34; 95%CI: 0.04 to 2.87). In the follow-up data, we found no association between age <= 2-year-old and arrhythmia (HR = 0.95; 95%CI: 0.50 to 1.80) and procedure-related arrhythmia (HR = 0.96;95%CI:0.25 to 3.64). Kaplan-Meier survival curves indicated no significant difference in the occurrence of arrhythmia between the 2 groups (log-rank test: p = 0.776). In conclusion, percutaneous ASD closure in young and low weight infants has a high success and low complication rate, along with reliable effects. (C) 2020 Published by Elsevier Inc.
机译：我们的目的是评估介入治疗2岁以下低体重婴儿房间隔缺损（ASD）的可行性。793例继发孔型ASD患者分为2组：665例2岁以上，128例2岁以下。采用多变量分析比较两组患者术前的基本情况、术后24小时内的并发症以及三年随访期间的不良结果。两组在年龄、体重和ASD直径方面存在显著差异（P0.001）。手术即刻成功率为96.7%。两组手术成功率、残余分流、心律失常、手术相关心律失常和封堵器脱落的发生率无显著差异（p0.05）。类似地，我们发现年龄≤2岁与术后24小时内的任何不良后果之间没有关联，包括手术失败（OR=0.35；95%可信区间：0.04至2.93）、残余分流（OR=1.07；95%可信区间：0.54至2.14）、心律失常（OR=0.68；95%可信区间：0.32至1.43）或手术相关心律失常（OR=0.34；95%可信区间：0.04至2.87）。在随访数据中，我们发现年龄≤2岁与心律失常（HR=0.95；95%可信区间：0.50至1.80）和手术相关心律失常（HR=0.96；95%可信区间：0.25至3.64）之间没有关联。Kaplan-Meier生存曲线显示两组之间心律失常发生率无显著差异（对数秩检验：p=0.776）。总之，在年轻和低体重婴儿中，经皮ASD封堵术成功率高，并发症发生率低，疗效可靠。（C） 2020年由爱思唯尔公司出版。

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  • 作者

    Cao Chunhui; Li Ren; Huang Jun; Zhao Yaqin; Wang Zhonghua; Xie Yumei; Wang Shushui; Zhou Rong; Lin Dongxin; Fan Lingxia; Wei Xianglong; Zhang Zhiwei;

  • 作者单位

    Southern Med Univ Shenzhen Hosp Dept Cardiol Shenzhen Guangdong Peoples R China;

    First Peoples Hosp Chenzhou Dept Cardiol Chenzhou Peoples R China;

    Southern Med Univ Shenzhen Hosp Dept Emergency Surg Shenzhen Guangdong Peoples R China;

    Southern Med Univ Shenzhen Hosp Dept Cardiol Shenzhen Guangdong Peoples R China;

    First Peoples Hosp Chenzhou Dept Cardiol Chenzhou Peoples R China;

    Guangdong Acad Med Sci Guangdong Cardiovasc Inst Dept Cardiac Pediat Guangdong Gen Hosp;

    Guangdong Acad Med Sci Guangdong Cardiovasc Inst Dept Cardiac Pediat Guangdong Gen Hosp;

    Southern Med Univ Shenzhen Hosp Dept Cardiol Shenzhen Guangdong Peoples R China;

    Southern Med Univ Foshan Inst Fetal Med Affiliated Maternal &

    Child Hlth Hosp Foshan Foshan;

    Chengdu Womens &

    Childrens Cent Hosp Dept Cardiol Chengdu Peoples R China;

    Southern Med Univ Shenzhen Hosp Dept Cardiol Shenzhen Guangdong Peoples R China;

    Guangdong Acad Med Sci Guangdong Cardiovasc Inst Dept Cardiac Pediat Guangdong Gen Hosp;

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  • 正文语种 eng
  • 中图分类 心脏、血管（循环系）疾病;
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