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首页> 外文期刊>The American Journal of Cardiology >Comparison of Complications and In-Hospital Mortality in Takotsubo (Apical Ballooning/Stress) Cardiomyopathy Versus Acute Myocardial Infarction
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Comparison of Complications and In-Hospital Mortality in Takotsubo (Apical Ballooning/Stress) Cardiomyopathy Versus Acute Myocardial Infarction

机译：Takotsubo（顶端气球/胁迫）心肌病与急性心肌梗死的并发症和住院死亡率的比较

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摘要

There are limited data on the incidence of complications and in-hospital outcomes, in patients with Takotsubo cardiomyopathy (TC), as compared with acute myocardial infarction (AMI). From 2007 to 2014, a retrospective cohort of TC was compared with AMI using the National Inpatient Sample database. Complications were classified as acute heart failure, ventricular arrhythmic, cardiac arrest, high-grade atrioventricular block, mechanical, vascular/access, pericardial, stroke, and acute kidney injury. Temporal trends, clinical characteristics, and in-hospital outcomes were compared. During the 8-year period, 3,329,876 admissions for AMI or TC were identified. TC diagnosis was present in 88,849 (2.7%). Compared with AMI admissions, those with TC were older, female, and of white race. Use of pulmonary artery catheter and mechanical ventilation was higher, but hemodialysis lower in TC. The overall frequency of complications was higher in TC (38.2% vs 32.6%). Complication rates increased in both groups over time, but the delta was greater for TC (23% [2007] vs 43% [2014]) compared with AMI (27% vs 36%). The TC cohort had a higher rate of heart failure (29% vs 16.6%) and strokes (0.5% vs 0.2%), but lower rates of other complications (all p <0.001). In-hospital mortality was lower for TC (2.6% vs 3.1%; p <0.001). TC was an independent predictor of lower in -hospital mortality in admissions with complications. In conclusion, compared with AMI, TC is associated with greater likelihood of heart failure, but lower rates of other complications and mortality. There has been a temporal increase in the rates of in-hospital complications and mortality due to TC. (C) 2020 Elsevier Inc. All rights reserved.
机译：与急性心肌梗死（AMI）相比，关于Takotsubo心肌病（TC）患者并发症发生率和住院结局的数据有限。从2007年到2014年，使用国家住院患者样本数据库对TC和AMI进行了回顾性队列比较。并发症分为急性心力衰竭、室性心律失常、心脏骤停、重度房室传导阻滞、机械性、血管/通路、心包、中风和急性肾损伤。比较时间趋势、临床特征和住院结果。在这8年期间，确定了3329876例AMI或TC入院病例。有88849例（2.7%）出现TC诊断。与AMI患者相比，TC患者年龄更大、女性、白人。TC患者使用肺动脉导管和机械通气的比例较高，但血液透析的比例较低。总的并发症发生率在TC组较高（38.2%比32.6%）。随着时间的推移，两组的并发症发生率都有所增加，但TC（23%[2007]vs 43%[2014]）与AMI（27%vs 36%）的差异更大。TC组的心力衰竭（29%对16.6%）和中风（0.5%对0.2%）发生率较高，但其他并发症发生率较低（均p<0.001）。TC的住院死亡率较低（2.6%比3.1%；p<0.001）。TC是并发症住院患者住院死亡率较低的独立预测因子。总之，与AMI相比，TC与心力衰竭的可能性更高，但其他并发症和死亡率更低。TC导致的院内并发症和死亡率暂时增加。（C） 2020爱思唯尔公司版权所有。

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