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首页> 外文期刊>The American Journal of Cardiology >Comparison of Outcomes of Alcohol Septal Ablation or Septal Myectomy for Hypertrophic Cardiomyopathy in Patients 65 Years
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Comparison of Outcomes of Alcohol Septal Ablation or Septal Myectomy for Hypertrophic Cardiomyopathy in Patients 65 Years

机译：65年患者肥厚性心肌病的酒精隔膜消融或隔膜肌切除术的结果比较

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摘要

Alcohol septal ablation (ASA) and septal myectomy (SM) are therapeutic interventions for patients with hypertrophic cardiomyopathy (HC) who remain symptomatic despite medical treatment. Outcomes for both interventions in age groups 65 years are scarce. We queried the National Readmission Database for adult patients undergoing either SM or ASA between 2010 and 2015 for HC. Patients were divided into 2 age-groups ( 65-years). We aimed to compare the in-hospital mortality, complication rates, and resource utilization for each procedure between the 2 age-groups. We identified 4,358 patients with HC who underwent intervention, of which 2,113 were treated with SM and 2,245 with ASA. In-hospital mortality was 6-times higher in patients 65 years treated with SM compared with ASA (6.7% vs 1.7% odds ratio 4.29; p = 0.04). Blood transfusion rates and stroke were higher in patients undergoing SM, regardless of their age-group. Length of hospital stay was lower in the ASA group (3 days vs 6 days for both age groups, p 65 years old: $16,672 vs $36,042, p <0.001). In conclusion, patients with HC treated with ASA had significantly lower inhospital mortality, complications rates, length of hospital stay, and hospital costs compared with patients undergoing SM at any age. (C) 2020 Elsevier Inc. All rights reserved.
机译：酒精间隔消融术（ASA）和间隔肌切除术（SM）是治疗肥厚型心肌病（HC）患者的干预措施，这些患者尽管接受了药物治疗，但仍有症状。这两种干预措施在65岁年龄组的效果都很差。我们查询了2010年至2015年间因HC接受SM或ASA治疗的成年患者的国家再入院数据库。患者分为两个年龄组（65岁）。我们的目的是比较两个年龄组的住院死亡率、并发症发生率和每种手术的资源利用率。我们确定了4358例接受干预的HC患者，其中2113例接受SM治疗，2245例接受ASA治疗。65岁接受SM治疗的患者的住院死亡率是ASA患者的6倍（6.7%对1.7%比值比4.29；p=0.04）。无论年龄组，接受SM治疗的患者的输血率和中风率都较高。ASA组的住院时间较短（两个年龄组分别为3天和6天，p 65岁：$16672和$36042，p<0.001）。总之，与任何年龄段接受SM治疗的患者相比，接受ASA治疗的HC患者的住院死亡率、并发症发生率、住院时间和住院费用显著降低。（C） 2020爱思唯尔公司版权所有。

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