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首页> 外文期刊>The International journal of pharmacy practice >A randomized comparative evaluation of clinical and home application to investigate the effectiveness of silver nitrate ( A A g NO NO 3 3 ) (95%) for the treatment of verruca pedis
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A randomized comparative evaluation of clinical and home application to investigate the effectiveness of silver nitrate ( A A g NO NO 3 3 ) (95%) for the treatment of verruca pedis

机译：临床和家庭应用的随机比较评估，探讨硝酸银（A G NO 3 3）（95％）治疗疣染料的效果

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Abstract Objective To investigate the clinical effectiveness of silver nitrate (95%) for the treatment of verruca pedis comparing professional and self‐application treatments. Methods A single‐centre, two‐armed randomized evaluation was conducted at a University podiatry clinic. A total of 113 participants (101 analysed) with verruca pedis were included. Participants were randomized to either a clinical group, where silver nitrate was applied by a healthcare professional or a home group, where silver nitrate was self‐applied. The main outcome measure was post‐treatment pain, controlling for pre‐treatment pain, and resolution of the verruca. Secondary outcome measures were participant satisfaction, partial reduction in the verruca and ease of use of the product. Key findings The study showed no significant difference between home treatment and clinically applied treatment for the treatment of verruca pedis in either primary outcome; however, a substantive difference in resolution between groups was recorded, with 34.0% full resolution and 26.4% partial resolution in the clinical treatment group, and 18.8% full resolution and 37.5% partial resolution in the home treatment group. Participants widely reported general ease of use of the product. All participants reported a reduction in pain as a result of the intervention. Conclusion Silver nitrate has been shown to be a safe and effective treatment for verruca pedis, with equal success rates when compared between home and clinical applications.
机译：摘要目的对比专业治疗和自我应用治疗，探讨硝酸银（95%）治疗足部疣的临床疗效。方法在一所大学足部诊所进行单中心、两臂随机评估。共有113名患有足部疣的参与者（101人接受了分析）。参与者被随机分为临床组（由医疗专业人员使用硝酸银）或家庭组（由个人使用硝酸银）。主要观察指标为治疗后疼痛、治疗前疼痛控制和疣体消退。次要结果指标是参与者满意度、疣的部分减少和产品的易用性。主要发现该研究表明，家庭治疗和临床应用治疗在治疗足部疣的两个主要结果方面没有显著差异；然而，两组之间的分辨率存在实质性差异，临床治疗组的完全分辨率为34.0%，部分分辨率为26.4%，家庭治疗组的完全分辨率为18.8%，部分分辨率为37.5%。参与者广泛报告了该产品的普遍易用性。所有参与者都报告说，干预后疼痛减轻。结论硝酸银是一种安全有效的治疗足部疣的方法，在家庭和临床应用中具有相同的成功率。

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