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首页> 外文期刊>Wilderness & environmental medicine >Retrieval of Additional Epinephrine from Adrenaclick-Style Epinephrine Autoinjectors
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Retrieval of Additional Epinephrine from Adrenaclick-Style Epinephrine Autoinjectors

机译：从肾上腺射出式肾上腺素自身注射器检索额外的肾上腺素

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摘要

Anaphylaxis is a life-threatening allergic reaction involving multiple organ systems that can result in significant morbidity and mortality if left untreated. Epinephrine is the mainstay of treatment. Most episodes of anaphylaxis resolve after a single dose of epinephrine, but biphasic and protracted courses of anaphylaxis are well described. The need for additional doses of epinephrine poses a significant challenge in the wilderness setting, because patients and providers may only carry a single autoinjector. Prior work has demonstrated successful disassembly of various brands of epinephrine autoinjectors to retrieve additional drug product for repeat dosing. We describe 2 techniques to retrieve additional doses of epinephrine from Adrenaclick-style epinephrine autoinjectors. The techniques described are off-label and are not approved by the manufacturer or the Food and Drug Administration. Wilderness providers should familiarize themselves with techniques for retrieval of additional epinephrine from various autoinjectors in light of significant differences in product design.
机译：过敏反应是一种危及生命的过敏反应，涉及多个器官系统，如果不进行治疗，可能会导致严重的发病率和死亡率。肾上腺素是治疗的主要药物。大多数过敏反应在单剂量肾上腺素后缓解，但双相和长期的过敏反应过程描述得很好。在野外环境中，需要额外剂量的肾上腺素是一个重大挑战，因为患者和提供者只能携带一个自动注射器。之前的工作已经证明，成功地拆卸了各种品牌的肾上腺素自动注射器，以回收用于重复给药的额外药品。我们描述了两种从肾上腺舔式肾上腺素自动注射器中提取额外剂量肾上腺素的技术。所描述的技术是标签外的，未经制造商或食品和药物管理局批准。鉴于产品设计的显著差异，供应商应熟悉从各种自动注射器中提取额外肾上腺素的技术。

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