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Depression among Adult HIV/AIDS Patients Attending ART Clinics at Aksum Town, Aksum, Ethiopia: A Cross-Sectional Study

机译:成人艾滋病毒/艾滋病患者在埃塞俄比亚Aksum镇参加艺术诊所的抑郁症:横断面研究

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Background. Depression is consistently associated with increased risk of Human Immunodeficiency Virus infection and poor antiretroviral treatment adherence. Though many factors have been reported as determinant factors of depression, site-specific evidence is needed to identify factors associated with depression among adults on antiretroviral treatment. Methods. An institution based cross-sectional study was carried out from March to May 2015 among 411 adults HIV/AIDS patients on ART clinic follow-up. Participants were selected using systematic random sampling techniques. Data were collected using chart review and interviewer-administered techniques. Both bivariable and multivariable logistic regressions were used to compute the statistical test associations by SPSS version-20. Variables with p value < 0.05 were considered as statistically significant. Results. Four hundred eleven patients with a mean age ± Standard Deviation of 36.1±9.2 years and with a total response rate of 97.6% were enrolled in the study. The prevalence of depression was 14.6% (95% CI, 10.90-18.2). Factors independently associated with depression were nonadherence to ART, eating two meals per day or less, having side effect of ART medication, being in the WHO Stage II or above of HIV/AIDS, and living alone with AOR (95% CI) of 3.3 (1.436, 7.759), 2.8 (1.382, 5.794), 4.7 (1.317,16.514), 2.8 (0.142, 0.786), and 2.4 (1.097, 5.429), respectively. Conclusion. Though the magnitude of depression was found relatively low, it was commonly observed as a mental health problem among adult patients with HIV/AIDS on ART. Programs on counseling and close follow-up of adherence to ART, drug side effects, and nutrition should be strengthened. Health facilities should link adult patients with HIV/AIDS who live alone to governmental and nongovernmental social supporter organizations.
机译:出身背景抑郁症始终与人类免疫缺陷病毒感染风险增加和抗逆转录病毒治疗依从性差有关。尽管有许多因素被报道为抑郁症的决定因素,但仍需要现场特定的证据来确定接受抗逆转录病毒治疗的成年人中与抑郁症相关的因素。方法。2015年3月至5月,对411名接受ART临床随访的成人HIV/AIDS患者进行了一项基于机构的横断面研究。参与者采用系统随机抽样技术进行选择。数据收集使用图表审查和采访者管理的技术。通过SPSS version-20,使用双变量和多变量logistic回归计算统计检验关联。p值<0.05的变量被认为具有统计学意义。后果研究纳入了411名患者,平均年龄±标准差为36.1±9.2岁,总有效率为97.6%。抑郁症患病率为14.6%(95%可信区间10.90-18.2)。与抑郁症独立相关的因素包括不遵守抗逆转录病毒疗法、每天吃两顿饭或更少、有抗逆转录病毒药物的副作用、处于世界卫生组织HIV/AIDS II期或以上、独自生活,AOR(95%CI)分别为3.3(1.436,7.759)、2.8(1.382,5.794)、4.7(1.317,16.514)、2.8(0.142,0.786)和2.4(1.097,5.429)。结论虽然抑郁症的程度相对较低,但在接受抗逆转录病毒治疗的成年艾滋病毒/艾滋病患者中,抑郁症通常被视为一种心理健康问题。应该加强有关咨询和密切跟踪ART、药物副作用和营养的项目。卫生设施应将独居的成年艾滋病毒/艾滋病患者与政府和非政府社会支持组织联系起来。

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