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Heartworm Q&A:What do I need to know about heat-treating samples?

机译:HEALWORM Q&A:关于热处理样品需要了解什么?

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摘要

One of the more interesting developments to arise recently in the area of diagnosing heart-worm disease is the use of heat treatment in testing. Researchers have found that applying heat to antigen-negative serum samples will sometimes cause antigensto "show up," reversing the negative result to positive. They suspect that antigens bind with heartworm antibodies that are also circulating in the blood, forming immune complexes thatarent detected by standard antigen tests, and heat breaks down these bonds.
机译:最近在诊断心脏蠕虫疾病方面出现的一个更有趣的进展是在检测中使用热处理。研究人员发现,加热抗原阴性血清样本有时会导致抗原“出现”,从而将阴性结果逆转为阳性。他们怀疑抗原与同样在血液中循环的心丝虫抗体结合,形成标准抗原检测无法检测到的免疫复合物,而热量会破坏这些结合。

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