Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample

Kendler Kenneth S.; Ohlsson Henrik; Sundquist Jan; Sundquist Kristina

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Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample

机译：瑞典国家样本中主要情感和精神病疾病的家庭遗传风险分数与遗传建筑

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IMPORTANCE Family and genetic approaches have traditionally been used to evaluate our diagnostic concepts. Using a novel method, the family genetic risk score (FGRS), can we validate the genetic architecture of major affective and psychotic disorders in a national Swedish sample?

机译：重要性家族和遗传学方法传统上用于评估我们的诊断概念。使用一种新的方法，即家庭遗传风险评分（FGRS），我们能在瑞典国家样本中验证主要情感和精神疾病的遗传结构吗？

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《JAMA psychiatry》 |2021年第7期|共9页
作者
Kendler Kenneth S.; Ohlsson Henrik; Sundquist Jan; Sundquist Kristina;
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Virginia Commonwealth Univ Virginia Inst Psychiat &

Behav Genet POB 980126 Richmond VA 23298 USA;

Lund Univ Ctr Primary Hlth Care Res Malmo Sweden;

Lund Univ Ctr Primary Hlth Care Res Malmo Sweden;

Lund Univ Ctr Primary Hlth Care Res Malmo Sweden;

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正文语种 eng
中图分类神经病学与精神病学;
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2. A comparison of genetic risk score with family history for estimating prostate cancer risk [J] . Brian T Helfand 亚洲男性学杂志（英文版） . 2016,第004期
3. Genetic and environmental determinants of violence risk in psychotic disorders: a multivariate quantitative genetic study of 1.8 million Swedish twins and siblings [J] . A Sariaslan, H Larsson, S Fazel Molecular Psychiatry . 2016,第9期

机译：精神疾病中暴力风险的遗传和环境决定因素：对180万瑞典双胞胎和兄弟姐妹的多元定量遗传研究
4. Triparental Families: A New Genetic-Epidemiological Design Applied to Drug Abuse, Alcohol Use Disorders, and Criminal Behavior in a Swedish National Sample [J] . Kendler Kenneth S., Ohtsson Henrik, Sundquist Jan, American journal of psychiatry . 2015,第6期

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6. Evaluation of Psychoeducation Programs to Increase Knowledge's Family Caregivers of People with Psychotic Disorders [C] . Farida Coralia, Siti Qodariah, Milda Yanuvianti, Social and Humanities Research Symposium . 2020

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7. Genetic Biomarkers of Psychiatric Disease: Discriminating Bipolar Disorder from Major Depressive Disorder with Polygenic Risk Scores [D] . ?Liebers, David T. 2020

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8. The patterns of family genetic risk scores for eleven major psychiatric and substance use disorders in a Swedish national sample [O] . Kenneth S. Kendler, Henrik Ohlsson, Jan Sundquist, 2021

机译：瑞典国家样本中11重大精神病和物质使用障碍的家庭遗传风险分数
9. Genetic and environmental determinants of violence risk in psychotic disorders: a multivariate quantitative genetic study of 1.8 million Swedish twins and siblings [O] . Sariaslan, A, Larsson, HL, Fazel, SF 2015

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10. Pathways and barriers to genetic testing and screening: Molecular genetics meets the high-risk family. Final report [R] . Duster, T. 1998

机译：基因检测和筛选的途径和障碍：分子遗传学符合高风险家庭。最终报告

Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample

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