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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Comparing the osteoconductive potential between tubular and cylindrical beta‐tricalcium phosphate scaffolds: An experimental study in rats
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Comparing the osteoconductive potential between tubular and cylindrical beta‐tricalcium phosphate scaffolds: An experimental study in rats

机译：比较管状和圆柱形β-β-磷酸盐支架之间的骨导电电位：大鼠的实验研究

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Abstract Beta‐tricalcium phosphate (β‐TCP) has been widely used for bone regeneration for many years. However, there are few studies on the osteoconduction ability of different shaped β‐TCP scaffolds. In this study, we compared the osteoconductive potential between the tubular and cylindrical β‐TCP scaffolds in long bone defect animal model. The results showed that more regenerated bone and a better healing property were observed in tubular group than that in cylindrical group. By hematoxylin‐eosin staining, the central part of the callus was more compacted in tubular group. And moreover, the increased osteocalcin and osterix expression were found in tubular group, suggesting more vigorous regeneration of bone defect. These results demonstrated that tubular β‐TCP scaffold would be more benefit to promote bone regeneration, indicating that tubular β‐TCP scaffold has a good potential for long bone defect repair in clinical practice. ? 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1934–1940, 2018.
机译：摘要多年来，β-磷酸三钙（β-TCP）被广泛用于骨再生。然而，关于不同形状的β-TCP支架的骨传导能力的研究很少。在这项研究中，我们比较了长骨缺损动物模型中管状和圆柱形β-TCP支架之间的骨传导电位。结果表明，管状骨组比圆柱形骨组有更多的再生骨和更好的愈合性能。苏木精-伊红染色显示，管状骨痂的中央部分更加紧密。此外，在管状组中发现骨钙素和osterix表达增加，表明骨缺损的再生更加活跃。这些结果表明，管状β-TCP支架更有利于促进骨再生，表明管状β-TCP支架在临床实践中具有良好的修复长骨缺损的潜力？2017威利期刊有限公司《生物医学材料研究》第B部分：Appl Biomater，106B:1934–1940，2018年。

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