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首页> 外文期刊>Journal of Biophotonics >Strain and elasticity imaging in compression optical coherence elastography: The two-decade perspective and recent advances
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Strain and elasticity imaging in compression optical coherence elastography: The two-decade perspective and recent advances

机译：压缩光学相干弹性成像的应变和弹性成像弹性室：两十年的观点和最近的进步

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摘要

Quantitative mapping of deformation and elasticity in optical coherence tomography has attracted much attention of researchers during the last two decades. However, despite intense effort it took similar to 15 years to demonstrate optical coherence elastography (OCE) as a practically useful technique. Similarly to medical ultrasound, where elastography was first realized using the quasi-static compression principle and later shear-wave-based systems were developed, in OCE these two approaches also developed in parallel. However, although the compression OCE (C-OCE) was proposed historically earlier in the seminal paper by J. Schmitt in 1998, breakthroughs in quantitative mapping of genuine local strains and the Young's modulus in C-OCE have been reported only recently and have not yet obtained sufficient attention in reviews. In this overview, we focus on underlying principles of C-OCE; discuss various practical challenges in its realization and present examples of biomedical applications of C-OCE. The figure demonstrates OCE-visualization of complex transient strains in a corneal sample heated by an infrared laser beam.
机译：近二十年来，光学相干层析成像中形变和弹性的定量映射引起了研究人员的广泛关注。然而，尽管付出了巨大的努力，光学相干弹性成像（OCE）作为一种实用的技术却花费了大约15年的时间。与医学超声类似，弹性成像最初是使用准静态压缩原理实现的，后来开发了基于剪切波的系统，在OCE中，这两种方法也并行开发。然而，尽管J.Schmitt在1998年的开创性论文中历史性地较早地提出了压缩OCE（C-OCE），但在C-OCE中真正的局部应变和杨氏模量的定量绘图方面的突破仅在最近才被报道，尚未在评论中得到足够的重视。在这篇综述中，我们关注C-OCE的基本原则；讨论其实现过程中的各种实际挑战，并给出C-OCE的生物医学应用示例。该图显示了OCE对红外激光束加热的角膜样本中复杂瞬态应变的可视化。

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