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首页> 外文期刊>Journal of Biophotonics >Angular optimization for cancer identification with circularly polarized light
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Angular optimization for cancer identification with circularly polarized light

机译：圆偏振光的癌症识别角度优化

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摘要

Depolarization of circularly polarized light scattered from biological tissues depends on structural changes in cell nuclei, which can provide valuable information for differentiating cancer tissues concealed in healthy tissues. In this study, we experimentally verified the possibility of cancer identification using scattering of circularly polarized light. We investigated the polarization of light scattered from a sliced biological tissue with various optical configurations. A significant difference between circular polarizations of light scattered from cancerous and healthy tissues is observed, which is sufficient to distinguish a cancerous region. The line-scanning experiments along a region incorporating healthy and cancerous parts indicate step-like behaviors in the degree of circular polarization corresponding to the state of tissues, whether cancerous or normal. An oblique and perpendicular incidence induces different resolutions for identifying cancerous tissues, which indicates that the optical arrangement can be selected according to the priority of resolution.
机译：来自生物组织的圆偏振光的去极化取决于细胞核的结构变化，这可以为鉴别隐藏在健康组织中的癌组织提供有价值的信息。在这项研究中，我们通过实验验证了利用圆偏振光散射识别癌症的可能性。我们研究了不同光学结构的切片生物组织散射光的偏振。观察到癌组织和健康组织散射光的圆偏振之间存在显著差异，这足以区分癌区。沿着包含健康和癌症部分的区域进行的线扫描实验表明，无论是癌组织还是正常组织，其圆极化程度都呈阶梯状。斜入射和垂直入射导致识别癌组织的分辨率不同，这表明可以根据分辨率的优先级选择光学排列。

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