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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Ultrasound‐guided polidocanol foam sclerotherapy for treating venous malformations
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Ultrasound‐guided polidocanol foam sclerotherapy for treating venous malformations

机译：超声引导的聚胆糖醇泡沫硬化治疗静脉畸形

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Abstract Aim To evaluate clinical and imaging outcomes after ultrasound (US)‐guided 3% polidocanol (POL) foam‐sclerotherapy of venous malformations (VMs). Methods We retrospectively evaluated consecutive VM cases over 1.5 years, with 6‐month follow‐up. US findings were used to classify VMs into four types depending upon extent of anechoic channels, connections to adjacent veins, and dysmorphism. Single or multiple needles were inserted depending upon lesion size, and used to inject up to 8 mL POL per session, every 2 to 4 weeks. We evaluated reduction in pain and swelling, lesion resolution on imaging, and patient satisfaction. Results There were 15, 24, 9, and 5 patients (total 53) with type I, II, III, and IV VMs, respectively. The average number of sessions was 5.3, 4.3, and 4, and the average amount of POL injected was 14.24 mL, 16.1 mL, and 23.2 mL for type I, II, III VMs, respectively. The number of sessions correlated with lesion volume ( P .0001). Imaging showed good resolution in 4/15, 18/24, 6/9, and 4/5 patients respectively with type I, II, III, and IV VMs. Patient satisfaction was not related to lesion type ( P = .1). ROC analyses showed cut‐off values of 4.9 mL lesion volume, three sessions, and 12 mL POL volume for patient satisfaction. At 6 months, 23 patients having pain had significant improvement ( P .00001). Local ( n ?=?30) and chest pain ( n ?=?2) were the only complications. Conclusions US‐guided sclerotherapy with 3% POL foam is safe and effective. Lesions with up to 50% anechoic areas had better resolution, without correlation with patient satisfaction.
机译：摘要目的评估超声（US）引导下3%聚多糖（POL）泡沫硬化治疗静脉畸形（VMs）后的临床和影像学结果。方法回顾性分析1.5年来连续发生的VM病例，并进行6个月的随访。根据消声通道的范围、与相邻静脉的连接和畸形，美国的研究结果将VMs分为四种类型。根据病变大小插入单针或多针，每2至4周一次，每次注射8毫升POL。我们评估了疼痛和肿胀的减轻程度、影像学上的病变分辨率以及患者满意度。结果I型、II型、III型和IV型VMs患者分别为15例、24例、9例和5例（共53例）。I型、II型和III型VMs的平均疗程数分别为5.3、4.3和4次，POL的平均注射量分别为14.24 mL、16.1 mL和23.2 mL。治疗次数与病变体积相关（P；0.0001）。成像显示，I型、II型、III型和IV型VMs患者的分辨率分别为4/15、18/24、6/9和4/5。患者满意度与病变类型无关（P=0.1）。ROC分析显示，患者满意度的临界值为4.9毫升病变体积、三个疗程和12毫升POL体积。在6个月时，23名疼痛患者有显著改善（P；00001）。局部（n？=30）和胸痛（n？=2）是唯一的并发症。结论3%POL泡沫在超声引导下硬化治疗是安全有效的。消声面积高达50%的病变具有更好的分辨率，与患者满意度无关。

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