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首页> 外文期刊>Journal of drugs in dermatology: JDD >Tolerability of Six Months Indirect Cold (Physical) Plasma Treatment of the Scalp for Hair Loss
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Tolerability of Six Months Indirect Cold (Physical) Plasma Treatment of the Scalp for Hair Loss

机译：六个月的耐受性间接冷（物理）血浆治疗头皮的脱发

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摘要

Androgenetic alopecia (AGA) is a chronic form of hair loss. Cold atmospheric (physical) plasma (CAP) is partly ionized gas with various widely researched effects on living tissues. CAP is an emerging treatment modality in dermatology with uses for chronic leg ulcer, actinic keratosis, warts, and other applications. Its previously demonstrated ability to induce stem cell differentiation in various cell types makes CAP a possible treatment option for AGA. Directly creating CAP on the scalp surface has drawbacks, but indirect CAP treatment-when a CAP-treated liquid is used as topical therapy-offers an alternative. In a clinical pilot study, we treated 14 patients with AGA using the indirect CAP method for three months (4 patients) and six months (10 patients). The indirect CAP treatment was well tolerated and while the primary goal of the study was not to assess efficacy, most patients reported improvement, and the investigator's assessment also showed improvement in most patients. Our findings create the foundation for longer, extensive trials to systematically assess the efficacy of indirect CAP treatment for AGA.
机译：雄激素性脱发（AGA）是一种慢性脱发。冷大气（物理）等离子体（CAP）是一种部分电离的气体，对活体组织有各种广泛研究的影响。CAP是皮肤病学中一种新兴的治疗方式，用于治疗慢性腿部溃疡、光化性角化病、疣和其他应用。其先前证明的在各种细胞类型中诱导干细胞分化的能力使CAP成为AGA的可能治疗选择。直接在头皮表面形成CAP有缺点，但当CAP处理过的液体用作局部治疗时，间接CAP处理提供了一种替代方法。在一项临床试验研究中，我们使用间接CAP方法治疗了14名AGA患者，分别治疗了3个月（4名患者）和6个月（10名患者）。间接CAP治疗耐受性良好，虽然本研究的主要目标不是评估疗效，但大多数患者报告有改善，研究者的评估也显示大多数患者有改善。我们的研究结果为长期、广泛的试验奠定了基础，系统地评估间接CAP治疗AGA的疗效。

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