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首页> 外文期刊>Journal of Exotic Pet Medicine >CLINICAL VALUE OF FRUCTOSAMINE MEASUREMENTS AND FRUCTOSAMINE-ALBUMIN RATIO IN HYPOGLYCEMIC FERRETS (MUSTELA PUTORILTS FURO)
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CLINICAL VALUE OF FRUCTOSAMINE MEASUREMENTS AND FRUCTOSAMINE-ALBUMIN RATIO IN HYPOGLYCEMIC FERRETS (MUSTELA PUTORILTS FURO)

机译：果胺胺测量和果壳胺 - 白蛋白比率在低血糖雪貂（Mustela Putorilts Furo）的临床价值

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摘要

The objective of this preliminary study was to establish a reference range for plasma fructosamine concentration and fructosamine-albumin ratio in healthy ferrets and to compare these reference intervals to values obtained from hypoglycemic ferrets. Fructosamine concentration has been shown to reflect blood glucose concentration over the previous 1 to 2 weeks in other animal species, and may be a useful indicator of chronic hypoglycemia in ferrets diagnosed with insulinoma. Plasma fructosamine was measured with an automated colorimetric assay using nitroblue tetrazolium. Thirty-two clinically healthy and 5 hypoglycemic ferrets were included in the study. The reference interval in healthy ferrets for fructosamine was 110 (98 to 123) - 203 (191 to 218) mu mol/L, and the reference interval for plasma fructosamine-albumin ratio was 5.1 (4.6 to 5.6) - 8.6 (8.2 to 9.0) mu mol/g. Results for hypoglycemic ferrets were within the ranges for both fructosamine and fructosamine-albumin ratio. As there were no significant differences between the healthy and hypoglycemic ferrets, this study suggests that fructosamine concentration and fructosamine-albumin ratio are not likely to be useful in determining insulinoma-associated chronic hypoglycemia in ferrets. Copyright 2018 Elsevier Inc. All rights reserved.
机译：本初步研究的目的是建立健康雪貂血浆果糖胺浓度和果糖胺白蛋白比率的参考范围，并将这些参考区间与从低血糖雪貂获得的值进行比较。果糖胺浓度已被证明反映了其他动物在过去1至2周内的血糖浓度，可能是诊断为胰岛素瘤的雪貂慢性低血糖的有用指标。血浆果糖胺用硝基蓝四氮唑自动比色法测定。32只临床健康的雪貂和5只低血糖雪貂被纳入研究。健康雪貂的果糖胺参考区间为110（98至123）-203（191至218）μmol/L，血浆果糖胺白蛋白比率参考区间为5.1（4.6至5.6）-8.6（8.2至9.0）μmol/g。低血糖雪貂的结果均在果糖胺和果糖胺白蛋白比率的范围内。由于健康雪貂和低血糖雪貂之间没有显著差异，本研究表明，果糖胺浓度和果糖胺白蛋白比率不太可能有助于确定雪貂胰岛素瘤相关的慢性低血糖。2018爱思唯尔公司版权所有。保留所有权利。

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