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首页> 外文期刊>Journal of Exotic Pet Medicine >HEPATIC ENCEPHALOPATHY IN A RED-TAILED BOA (BOA CONSTRICTOR IMPERATOR)
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HEPATIC ENCEPHALOPATHY IN A RED-TAILED BOA (BOA CONSTRICTOR IMPERATOR)

机译：红尾良好的肝脏脑病（好的Charricticor Imperator）

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A 5-year-old female red-tailed boa (Boa constrictor imperator) was presented for abnormal neurologic behavior. Ultrasound examination revealed an enlarged liver, with rounded margins and hypoechoic areas. A complete snake virus polymerase chain reaction (PCR) profile was performed together with diagnostic blood testing. The snake virus PCR profile results were negative. Supportive treatment for the patient consisted of fluid therapy and nutritional support, supplemented with carnitine. Lactulose was administered orally every 24 hours. The snake died 3 weeks after the initial presentation. Histopathological examination of the liver showed extensive necrotic degeneration with hepatocytic centrilobular organization and cholestasis. Histopathology of the central nervous system (CNS) revealed a degenerative pattern of neurons, and a hyperplastic aspect of the microglial cells, morphologically similar to Alzheimer type II astrocytes. The postmortem examination results indicate that the neurological signs were a consequence of hepatic encephalopathy (HE). Reptiles with hepatic disease may show a wide variety of clinical signs. The last stage of liver diseases is often HE. Diagnostic procedures include hematology, serum/plasma biochemistry, echography, and biopsy. The prognosis for a patient that is presented with clinical signs of HE is guarded at best. Recommended treatment for reptile patients that are diagnosed with HE is fluid support and more specific hepatic therapeutic agents, including lactulose, silymarin, and carnitine. Copyright 2017 Elsevier Inc. All rights reserved.
机译：一只5岁的雌性红尾蟒（蟒蛇首领）因神经行为异常而被报告。超声检查显示肝脏肿大，边缘呈圆形，低回声区。进行了完整的蛇病毒聚合酶链反应（PCR）分析和诊断性血液检测。蛇病毒PCR图谱结果为阴性。患者的支持治疗包括液体疗法和营养支持，并辅以肉碱。乳果糖每24小时口服一次。这条蛇在初次出现3周后死亡。肝脏组织病理学检查显示广泛坏死性变性，伴有肝细胞小叶中心组织和胆汁淤积。中枢神经系统（CNS）的组织病理学显示神经元退化，小胶质细胞增生，形态类似于阿尔茨海默病II型星形胶质细胞。尸检结果表明，神经症状是肝性脑病（HE）的结果。患有肝病的爬行动物可能表现出多种临床症状。肝病的最后阶段通常是HE。诊断程序包括血液学、血清/血浆生物化学、超声和活检。对于出现HE临床症状的患者，预后最好是谨慎的。对于确诊为HE的爬行动物患者，推荐的治疗方法是液体支持和更具体的肝脏治疗药物，包括乳果糖、水飞蓟素和肉碱。2017爱思唯尔有限公司版权所有。

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